Supplementary information
From the following article:
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
Xin Zeng, Keiko Tamai, Brad Doble, Shitao Li, He Huang, Raymond Habas, Heidi Okamura, Jim Woodgett & Xi He
Nature 438, 873-877(8 December 2005)
doi:10.1038/nature04185
Supplementary Figure 1
A PPPSP kinase is associated with GST-LRP6C.
Supplementary Figure 2
A PPPSP kinase is associated with Axin.
Supplementary Figure 3
The specificity of Ab1493 for site II.
Supplementary Figure 4
The specificity of Ab1493 is independent of site I.
Supplementary Methods
Additional details of the methods used in this study.
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-/- MEFs.