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Nature 438, 571-573 (1 December 2005) | doi:10.1038/438571a; Published online 30 November 2005
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Associate Professor / Professor ? NCRIS TERN Director
- University Of Queensland, Australia
- Brisbane, Queensland, Australia
Molecular & Human Genetics
- Indian Institute of Chemical Biology
- Kolkata India
Cell biology: Protein choreography
Mara C. Duncan1 & Gregory S. Payne1
Abstract
Just under the cell surface, proteins engage in an intricate ballet to drive a transport process called endocytosis. Much is known about the individual dancers, but now the choreography is revealed.
Endocytosis is the process by which cells gulp up small patches of their outer plasma membrane, sucking them inside to form small membrane-enclosed vesicles. These bubble-like structures provide a transport mechanism for carrying proteins that were embedded in the outer membrane, extracellular molecules associated with some of those proteins and small amounts of extracellular fluid1.
- Mara C. Duncan and Gregory S. Payne are in the Department of Biological Chemistry, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA.
Correspondence to: Mara C. Duncan1 Email: mduncan@mednet.ucla.edu
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