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Nature 438, 566-567 (1 December 2005) | doi:10.1038/438566a; Published online 30 November 2005
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Assistant Professor of Medicine
- Massachusetts General Hospital
- Boston, MA
Senior Scientific Manager / Chief Scientific Manager for Neuroscience Group In Vivo Pharmacology / Biology
- Syngene International
- Bangalore, Karnataka 560099 India
Biophysics: Assembly line inspection
Sarah A. Woodson1
Abstract
Many of the biochemical events that occur in a cell are performed by huge complexes of proteins and nucleic acids. A cunning approach promises to show how the components convene to make a functioning 'machine'.
The cell's macromolecular machines contain dozens or even hundreds of components. But unlike man-made machines, which are built on assembly lines, these cellular machines assemble spontaneously from their protein and nucleic-acid components.
- Sarah A. Woodson is in the T. C. Jenkins Department of Biophysics, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA.
Email: swoodson@jhu.edu
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