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News and Views
Nature 438, 437-439 (24 November 2005) | doi:10.1038/438437a; Published online 23 November 2005
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Histocompatibility: Colonial match and mismatch
Gary W. Litman1
Abstract
Distinguishing self from non-self is the underlying basis of immunity. Intriguingly, the genetic system that governs a natural process akin to tissue transplantation in vertebrates has been characterized in an invertebrate.
On page 454 of this issue, a remarkable paper by De Tomaso and colleagues1 describes discoveries on two different fronts. The authors' subject of study is a small marine organism, a tunicate called Botryllus schlosseri (Fig. 1
- Gary W. Litman is at the Children's Research Institute, 830 First Street South, St Petersburg, Florida 33701, USA.
Email: litmanG@allkids.org
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