Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 438, 167-168 (10 November 2005) | doi:10.1038/438167a; Published online 9 November 2005
Open Innovation Challenges
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
nature jobs
Faculty Position - Center for Viral Oncology
- University of Kansas Medical Center
- Kansas City, KS
Senior Lecturer / Reader
- King's College London
- London United Kingdom
Neurobiology: Triggers for channel opening
Cynthia Czajkowski1
Abstract
Fast transmission between nerve cells relies on specialized ion channels. Probing the structure of these proteins reveals how the binding of a neurotransmitter causes the communication channels to open.
Chemical signalling in the brain involves the rapid opening and closing of channels known as ligand-gated ion channels, which lie in the membranes of nerve cells. Binding of a specific activator (a ligand) to these proteins triggers the opening of an integral pore through the membrane in as little as tens of microseconds1.
- Cynthia Czajkowski is in the Department of Physiology, University of Wisconsin-Madison, 601 Science Drive, Madison, Wisconsin 53711, USA.
Email: czajkowski@physiology.wisc.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Neurobiology Snails, synapses and smokersNature News and Views (17 May 2001)
Crystallizing our understanding of partial agonistsNature Neuroscience News and Views (01 Aug 2003)
See all 3 matches for News And ViewsRESEARCH
Genetic variation in the vulnerable and endemic Monkey Puzzle tree, detected using RAPDsHeredity Original Article
A stepwise mechanism for acetylcholine receptor channel gatingNature Letters to Editor (19 Apr 2007)
See all 31 matches for Research
