Supplementary information

From the following article:

SERRATE coordinates shoot meristem function and leaf axial patterning in Arabidopsis

Stephen P. Grigg, Claudia Canales, Angela Hay & Miltos Tsiantis

Nature 437, 1022-1026(13 October 2005)

doi:10.1038/nature04052

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Supplemntary Figure S1

A schematic of the SE genomic locus indicating the positions of lesions in se mutant alleles, and contains information regarding transcripts produced by these alleles.

Supplementary Figure S2

RT-PCR and RNA gel blot analysis of expression of various transcripts in se-3 and Col, and contains descriptions of PCR conditions and primer sequences.

Supplementary Figure S3

A histogram reflecting the cytosine methylation status of a region of the PHB genomic locus in se-3 and Col. Clones generated from se-3 show reduced levels of CpG methylation.

Supplementary Figure S4

Gene expression analysis of the gibberellic acid biosynthetic gene GA5, demonstrating that this gene is similarly regulated in a KNOX gain-of-function line, a dominant phb mutant, and se-1.

Supplementary Methods

Experimental procedures used in generation of the supporting online material not included in the main methods section.

Supplementary Table S1

A sequence alignment of all clones analysed for generating bisulphite sequencing data presented in Supplementary Figure S3.

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