Table of contents


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Editorials

Reaching for the Moon p789

Naive or not, NASA's next shot at landing on the Moon can succeed only if it is launched as a genuinely international collaboration.

doi: 10.1038/437789a


In need of rehab p789

The reputation of one of the world's most respected regulatory agencies is on the wane.

doi: 10.1038/437789b


Welcome Nature Physics p790

The launch of a new Nature journal comes at an exciting time for physics.

doi: 10.1038/437790a


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Research Highlights

Research highlights p792

doi: 10.1038/437792a


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News

The 1918 flu virus is resurrected p794

The recreation of one of the deadliest diseases known could help us to prevent another pandemic. Or it might trigger one, say critics. Andreas von Bubnoff investigates whether the benefits outweigh the risks.

doi: 10.1038/437794a

See also: Editor's summary


Sidelines p796

doi: 10.1038/437796a


Japan jumps towards personalized medicine p796

Desktop-device uses advanced DNA chip to analyse patient's blood.

David Cyranoski

doi: 10.1038/437796b


Q marks the spot as ancient sculptures yield their origins p797

Hopes raised that discovery will save Mayan site from local destruction.

Alexandra Witze

doi: 10.1038/437797a


Electric current captures top sperm p799

Technique leads to birth of healthy baby after other methods fail.

Carina Dennis

doi: 10.1038/437799a


Australia mooted as dump for world's nuclear waste p799

Former prime minister suggests uranium by-products could subsidize environmental projects.

Carina Dennis

doi: 10.1038/437799b


Physics prize puts spotlight on optics p800

Understanding quantum nature of light led to breakthroughs.

Jim Giles

doi: 10.1038/437800a


California prepares to roll out stem-cell funding p800

Cash may soon be flowing despite legal challenges.

Rex Dalton

doi: 10.1038/437800b


Gut feeling secures medical Nobel for Australian doctors p801

Microbiologists win for proving link between bacteria and stomach ulcers.

Alison Abbott

doi: 10.1038/437801a


News in brief p802

doi: 10.1038/437802a


News in Brief: Correction p803

doi: 10.1038/437803a


News in Brief: Clarification p803

doi: 10.1038/437803b


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News Features

Ornithology: Flight of the navigators p804

The Arctic is a unique testing ground for studying how birds navigate long distances. Jane Qiu catches up with an expedition to unravel the signals that help birds on their migrations.

doi: 10.1038/437804a

See also: Editor's summary


American Chemical Society: Chemical reaction p807

The friction that arises when a scientific society aims both to serve its members and stay commercially competitive is generating heat within the American Chemical Society. Emma Marris takes the society's temperature.

doi: 10.1038/437807a


Fetal-cell therapy: Paper chase p810

Thousands of patients are queueing to be treated by Hongyun Huang at his Beijing clinic. But no Western journal editor seems willing to publish his research. David Cyranoski talks to the neurosurgeon whose global reputation among the ailing hasn't swayed his peers.

doi: 10.1038/437810a

See also: Editor's summary


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Business

Innovation endgame p813

The commercial practices of some universities are quietly being transformed by an international chess grandmaster, as Jim Giles reports.

doi: 10.1038/437813a


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Correspondence

Media should campaign on the basis of facts p814

Robert May

doi: 10.1038/437814a


No evidence for Croatian race claims p814

Dragan Primorac

doi: 10.1038/437814b


Katrina: don't blame the Bush administration p814

Stephen F. Larner

doi: 10.1038/437814c


Katrina revealed need for reform. Let's not forget it p814

Alison Chaiken

doi: 10.1038/437814d


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Books and Arts

A secular religion p815

Should evolutionism be viewed as a modified descendant of Christianity?

John Hedley Brooke reviews The Evolution−Creation Struggle by Michael Ruse

doi: 10.1038/437815a


The rise of the computer p816

Anthony Ralston reviews Electronic Brains: Stories from the Dawn of the Computer Age by Mike Hally

doi: 10.1038/437816a

See also: Editor's summary


Exhibition: Lighting up the background p817

doi: 10.1038/437817a


A philosopher's vision p817

Richard L. Gregory reviews Action in Perception by Alva Noë

doi: 10.1038/437817b


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Essay

A quantum recipe for life p819

Sixty years on, Erwin Schrödinger's prediction that quantum mechanics would solve the riddle of how life started has not been fulfilled. But the appeal of using quantum theory to solve the mystery persists.

Paul Davies

doi: 10.1038/437819a


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News and Views

Microbiology: Loading the type III cannon p821

Many pathogenic bacteria possess a secretion machine that shoots noxious proteins into host cells. But the ammunition is larger than the bore of the bacterial gun, so how is it fed into the machine?

Bill Blaylock and Olaf Schneewind

doi: 10.1038/437821a


Astrophysics: Short-burst sources p822

Measurements of the X-ray afterglow of long gamma-ray bursts largely clarified the origin of these bright flashes of cosmic radiation. Their shorter-lived siblings are now beginning to divulge their secrets, too.

Luigi Piro

doi: 10.1038/437822a

See also: Editor's summary


Microbiology: Conspirators in blight p823

A fungus and a bacterium have been found in a symbiotic alliance that attacks rice plants. Rice feeds more people than any other crop, but the significance of this finding extends beyond its potential agricultural use.

Ian R. Sanders

doi: 10.1038/437823a

See also: Editor's summary


50 & 100 years ago p824

doi: 10.1038/437824a


Condensed-matter physics: Melted by mistakes p824

Two-dimensional polymers are potentially useful structures — if we could only understand their properties. Observations of one polymer's intricate, two-stage, melting transition may help us do just that.

Edward J. Kramer

doi: 10.1038/437824b


Ecology: Stars beneath the waves p826

David W. Sims

doi: 10.1038/437826a


Palaeobiology: Sea change in sediments p826

Earth's oxygen levels increased slowly over a long and ill-defined transitional period around two billion years ago. A microbial 'footprint' from this era provides biological evidence to complement existing geological data.

David J. Des Marais

doi: 10.1038/437826b

See also: Editor's summary


Obituary: Hermann Bondi (1919−2005) p828

Mathematician, cosmologist and public servant.

Leon Mestel

doi: 10.1038/437828a


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Brief Communications

Entomology: Asian honeybees parasitize the future dead p829

When a queen dies, unrelated workers seize the chance to move into her nest and lay their own eggs.

Piyamas Nanork, Jürgen Paar, Nadine C. Chapman, Siriwat Wongsiri and Benjamin P. Oldroyd

doi: 10.1038/437829a

See also: Editor's summary


Seismology: Dynamic triggering of earthquakes p830

Joan Gomberg and Paul Johnson

doi: 10.1038/437830a

See also: Editor's summary


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Articles

Structure of the CED-4−CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans p831

Nieng Yan, Jijie Chai, Eui Seung Lee, Lichuan Gu, Qun Liu, Jiaqing He, Jia-Wei Wu, David Kokel, Huilin Li, Quan Hao, Ding Xue and Yigong Shi

doi: 10.1038/nature04002


Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme p838

Luke J. Higgins, Feng Yan, Pinghua Liu, Hung-wen Liu and Catherine L. Drennan

doi: 10.1038/nature03924

See also: Editor's summary


The afterglow of GRB 050709 and the nature of the short-hard bold gamma-ray bursts p845

D. B. Fox, D. A. Frail, P. A. Price, S. R. Kulkarni, E. Berger, T. Piran, A. M. Soderberg, S. B. Cenko, P. B. Cameron, A. Gal-Yam, M. M. Kasliwal, D.-S. Moon, F. A. Harrison, E. Nakar, B. P. Schmidt, B. Penprase, R. A. Chevalier, P. Kumar, K. Roth, D. Watson, B. L. Lee, S. Shectman, M. M. Phillips, M. Roth, P. J. McCarthy, M. Rauch, L. Cowie, B. A. Peterson, J. Rich, N. Kawai, K. Aoki, G. Kosugi, T. Totani, H.-S. Park, A. MacFadyen and K. C. Hurley

doi: 10.1038/nature04189

See also: Editor's summary


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Letters

A short bold gamma-ray burst apparently associated with an elliptical galaxy at redshift z = 0.225 p851

N. Gehrels, C. L. Sarazin, P. T. O'Brien, B. Zhang, L. Barbier, S. D. Barthelmy, A. Blustin, D. N. Burrows, J. Cannizzo, J. R. Cummings, M. Goad, S. T. Holland, C. P. Hurkett, J. A. Kennea, A. Levan, C. B. Markwardt, K. O. Mason, P. Meszaros, M. Page, D. M. Palmer, E. Rol, T. Sakamoto, R. Willingale, L. Angelini, A. Beardmore, P. T. Boyd, A. Breeveld, S. Campana, M. M. Chester, G. Chincarini, L. R. Cominsky, G. Cusumano, M. de Pasquale, E. E. Fenimore, P. Giommi, C. Gronwall, D. Grupe, J. E. Hill, D. Hinshaw, J. Hjorth, D. Hullinger, K. C. Hurley, S. Klose, S. Kobayashi, C. Kouveliotou, H. A. Krimm, V. Mangano, F. E. Marshall, K. McGowan, A. Moretti, R. F. Mushotzky, K. Nakazawa, J. P. Norris, J. A. Nousek, J. P. Osborne, K. Page, A. M. Parsons, S. Patel, M. Perri, T. Poole, P. Romano, P. W. A. Roming, S. Rosen, G. Sato, P. Schady, A. P. Smale, J. Sollerman, R. Starling, M. Still, M. Suzuki, G. Tagliaferri, T. Takahashi, M. Tashiro, J. Tueller, A. A. Wells, N. E. White and R. A. M. J. Wijers

doi: 10.1038/nature04142

See also: Editor's summary


Discovery of the short bold italic gamma-ray burst GRB 050709 p855

J. S. Villasenor, D. Q. Lamb, G. R. Ricker, J.-L. Atteia, N. Kawai, N. Butler, Y. Nakagawa, J. G. Jernigan, M. Boer, G. B. Crew, T. Q. Donaghy, J. Doty, E. E. Fenimore, M. Galassi, C. Graziani, K. Hurley, A. Levine, F. Martel, M. Matsuoka, J.-F. Olive, G. Prigozhin, T. Sakamoto, Y. Shirasaki, M. Suzuki, T. Tamagawa, R. Vanderspek, S. E. Woosley, A. Yoshida, J. Braga, R. Manchanda, G. Pizzichini, K. Takagishi and M. Yamauchi

doi: 10.1038/nature04213

See also: Editor's summary


The optical afterglow of the short bold gamma-ray burst GRB 050709 p859

Jens Hjorth, Darach Watson, Johan P. U. Fynbo, Paul A. Price, Brian L. Jensen, Uffe G. Jørgensen, Daniel Kubas, Javier Gorosabel, Páll Jakobsson, Jesper Sollerman, Kristian Pedersen and Chryssa Kouveliotou

doi: 10.1038/nature04174

See also: Editor's summary


Microscopic artificial swimmers p862

Rémi Dreyfus, Jean Baudry, Marcus L. Roper, Marc Fermigier, Howard A. Stone and Jérôme Bibette

doi: 10.1038/nature04090

See also: Editor's summary


Biomarker evidence for green and purple sulphur bacteria in a stratified Palaeoproterozoic sea p866

Jochen J. Brocks, Gordon D. Love, Roger E. Summons, Andrew H. Knoll, Graham A. Logan and Stephen A. Bowden

doi: 10.1038/nature04068

See also: Editor's summary


Nonlinear dynamics, granular media and dynamic earthquake triggering p871

Paul A. Johnson and Xiaoping Jia

doi: 10.1038/nature04015

See also: Editor's summary


Pterosaur diversity and faunal turnover in Cretaceous terrestrial ecosystems in China p875

Xiaolin Wang, Alexander W. A. Kellner, Zhonghe Zhou and Diogenes de Almeida Campos

doi: 10.1038/nature03982

See also: Editor's summary


Trophic cascades across ecosystems p880

Tiffany M. Knight, Michael W. McCoy, Jonathan M. Chase, Krista A. McCoy and Robert D. Holt

doi: 10.1038/nature03962

See also: Editor's summary


Pathogenic fungus harbours endosymbiotic bacteria for toxin production p884

Laila P. Partida-Martinez and Christian Hertweck

doi: 10.1038/nature03997

See also: Editor's summary


Characterization of the 1918 influenza virus polymerase genes p889

Jeffery K. Taubenberger, Ann H. Reid, Raina M. Lourens, Ruixue Wang, Guozhong Jin and Thomas G. Fanning

doi: 10.1038/nature04230

See also: Editor's summary


In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog p894

Sohyun Ahn and Alexandra L. Joyner

doi: 10.1038/nature03994

See also: Editor's summary


Sex-specific peptides from exocrine glands stimulate mouse vomeronasal sensory neurons p898

Hiroko Kimoto, Sachiko Haga, Koji Sato and Kazushige Touhara

doi: 10.1038/nature04033

See also: Editor's summary


STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane p902

Shenyuan L. Zhang, Ying Yu, Jack Roos, J. Ashot Kozak, Thomas J. Deerinck, Mark H. Ellisman, Kenneth A. Stauderman and Michael D. Cahalan

doi: 10.1038/nature04147


Apolipoprotein-mediated pathways of lipid antigen presentation p906

Peter van den Elzen, Salil Garg, Luis León, Manfred Brigl, Elizabeth A. Leadbetter, Jenny E. Gumperz, Chris C. Dascher, Tan-Yun Cheng, Frank M. Sacks, Petr A. Illarionov, Gurdyal S. Besra, Sally C. Kent, D. Branch Moody and Michael B. Brenner

doi: 10.1038/nature04001

See also: Editor's summary


Chaperone release and unfolding of substrates in type III secretion p911

Yukihiro Akeda and Jorge E. Galán

doi: 10.1038/nature03992


Direct observation of steps in rotation of the bacterial flagellar motor p916

Yoshiyuki Sowa, Alexander D. Rowe, Mark C. Leake, Toshiharu Yakushi, Michio Homma, Akihiko Ishijima and Richard M. Berry

doi: 10.1038/nature04003


Erratum: Deficiency of glutaredoxin 5 reveals Fe−S clusters are required for vertebrate haem synthesis p920

Rebecca A. Wingert, Jenna L. Galloway, Bruce Barut, Helen Foott, Paula Fraenkel, Jennifer L. Axe, Gerhard J. Weber, Kimberly Dooley, Alan J. Davidson, Bettina Schmid, Barry H. Paw, George C. Shaw, Paul Kingsley, James Palis, Heidi Schubert, Opal Chen, Jerry Kaplan, The Tübingen 2000 Screen Consortium and Leonard I. Zon

doi: 10.1038/nature04218


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Naturejobs

Prospect

Out in the cold p921

Despite some programmes, minorities in US science remain under-represented

Paul Smaglik

doi:10.1038/nj7060-921a


Postdocs and Students

To do today p922

Moving research quickly forward to publication tops the pre-tenure 'to do' list. Kendall Powell ticks off project management tips.

Kendall Powell

doi:10.1038/nj7060-922a


Career Views

Geoffrey West, president, Santa Fe Institute, Santa Fe, New Mexico p924

Theoretical physicist aims to create ideal interdisciplinary environment

Virginia Gewin

doi:10.1038/nj7060-924a


Recruiters & Academia p924

Multitasking can lead to alternative career paths

Santa Jeremy Ono

doi:10.1038/nj7060-924b


Graduate Journal: A time to reconnect p924

Taking a break, setting priorities

Tobias Langenhan

doi:10.1038/nj7060-924c


Highlights

Special Feature: Life in the NIH Intramural Research Program: Great Colleagues, Grand Possibilities, Cutting Edge Technology

doi:10.1038/nj0098


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Futures

Sandcastles: a dystopia p926

Caught up in a storm.

Kathryn Cramer

doi: 10.1038/437926a


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