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Nature 437, 491-493 (22 September 2005) | doi:10.1038/437491a; Published online 21 September 2005
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Head-Preclinical
- Syngene International
- Bangalore, Karnataka 560099 India
Head of Formulation R&D
- Syngene International Limited
- Bangalore 560 099 India
Pharmaceuticals: A new grammar for drug discovery
Mark C. Fishman1 & Jeffery A. Porter1
Abstract
To realize the potential of the genome for identifying candidate drugs we must move beyond individual genes and proteins. The signalling pathways in cells provide the right level for such analyses.
Drug discovery is a tough business scientifically, the traditional steps taking nearly a decade. In this article we are concerned only with the very beginning of the process, the identification of a target for a new drug.
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