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Nature 437, 203-205 (8 September 2005) | doi:10.1038/437203a; Published online 7 September 2005

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Molecular physiology: Intimate contact enables transport

Baruch I. Kanner1

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Sodium-coupled neurotransmitter transporters are essential for neurons to communicate. The high-resolution crystal structure of a bacterial relative hints at how this family of transporters works.

Ion-coupled transporters are essential for all forms of life. These molecular machines carry their cargoes across membranes to help accumulate foodstuffs in cells, maintain cellular pH levels and facilitate communication between nerve cells.

  1. Baruch I. Kanner is in the Department of Biochemistry, Hebrew University Hadassah Medical School, PO Box 12272, Jerusalem 91120, Israel.
    Email: kannerb@cc.huji.ac.il

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