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From the following article:
The most infectious prion protein particles
Jay R. Silveira, Gregory J. Raymond, Andrew G. Hughson, Richard E. Race, Valerie L. Sim, Stanley F. Hayes and Byron Caughey
Nature 437, 257-261 (8 September 2005)
doi: 10.1038/nature03989
Figure 3
Transmission electron microscopy analyses of fractionated PrPres.
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