Supplementary information

From the following article:

Ipr1 gene mediates innate immunity to tuberculosis

Hui Pan, Bo-Shiun Yan, Mauricio Rojas, Yuriy V. Shebzukhov, Hongwei Zhou, Lester Kobzik, Darren E. Higgins, Mark J. Daly, Barry R. Bloom and Igor Kramnik

Nature 434, 767-772(7 April 2005)

doi:10.1038/nature03419

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Supplementary Figure S1

Tuberculosis lung lesions in the sst1R and the sst1S congenic mouse strains after aerosol infection with MTB

Supplementary Figure S2

MTB growth in the organs of the sst1 congenic mouse strains and bone marrow chimeras after systemic i.v. infection

Supplementary Figure S3

Analysis of the sst1 minimal region

Supplementary Figure Legends

Legends to accompany the above Supplementary Figures

Supplementary Table S1

List of all known and predicted genes within the sst1 minimal region

Supplementary Data

Identification of a candidate gene within the sst1 locus

Supplementary Methods

Additional details of methods used in this study.

Supplementary Notes

Nramp1 alleles of the inbred mouse strains used in the study and TUNEL staining of the tuberculosis lung lesions of the sst1R and sst1S congenic mice

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