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Nature 434, 29-31 (3 March 2005) | doi:10.1038/434029a; Published online 2 March 2005

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Evolutionary biology:  The hydrogenosome's murky past

Michael W. Gray1

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The evolution of specialized cellular powerhouses called hydrogenosomes has long confounded biologists. The discovery that in some cases they have their own genome sheds some much-needed light on the issue.

Hydrogenosomes are double-membraned subcellular structures that generate hydrogen while making the energy-storage compound ATP. They are found in certain eukaryotic (nucleus-containing) microbes that inhabit oxygen-deficient environments1.

  1. Michael W. Gray is in the CIAR Program in Evolutionary Biology, and the Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 1X5, Canada.
    e-mail: Email: m.w.gray@dal.ca

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