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Nature 433, 467-468 (3 February 2005) | doi:10.1038/433467a; Published online 2 February 2005
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Cell biology: Holding sisters for repair
Tatsuya Hirano1
Abstract
When a DNA molecule breaks, its complementary copy can be used as a template for repair. A familiar protein complex is recruited to the damaged site, keeping it close to the undamaged copy.
Before a cell divides, it must replicate its DNA, producing two identical copies of each chromosome, known as sister chromatids. When one of the sister chromatids suffers a break that affects both of its DNA strands, it is mended by 'homologous recombination'.
- Tatsuya Hirano is at the Cold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, New York 11724, USA.
e-mail: Email: hirano@cshl.edu
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