Access
To read this story in full you will need to login or make a payment (see right).
Insight
Nature 432, 846-854 (16 December 2004) | doi:10.1038/nature03196; Published online 15 December 2004
Open Innovation Challenges
- More Challenges
- Powered by:
nature jobs
Instrumentation Engineer
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
Chemical Process Engineer
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
review article Exploring biology with small organic molecules
Brent R. Stockwell1
Abstract
Small organic molecules have proven to be invaluable tools for investigating biological systems, but there is still much to learn from their use. To discover and to use more effectively new chemical tools to understand biology, strategies are needed that allow us to systematically explore 'biological-activity space'. Such strategies involve analysing both protein binding of, and phenotypic responses to, small organic molecules. The mapping of biological-activity space using small molecules is akin to mapping the stars — uncharted territory is explored using a system of coordinates that describes where each new feature lies.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Chemical biology Renewing embryonic stem cellsNature News and Views (07 Dec 2006)
Fishing and frogging for anti-angiogenic drugsNature Chemical Biology News and Views (01 May 2006)
See all 5 matches for News And Views