Access
To read this story in full you will need to login or make a payment (see right).
Insight
Nature 432, 855-861 (16 December 2004) | doi:10.1038/nature03193; Published online 15 December 2004
Open Innovation Challenges
-
Methods to Analyze Consumer Emotions
The Seeker is looking for methods to analyze consumer emotions. This Challenge requires only a writ...
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
- More Challenges
- Powered by:
nature jobs
Instrumentation Engineer
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
Natural Products Chemist
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
review article Navigating chemical space for biology and medicine
Christopher Lipinski1 & Andrew Hopkins2
Abstract
Despite over a century of applying organic synthesis to the search for drugs, we are still far from even a cursory examination of the vast number of possible small molecules that could be created. Indeed, a thorough examination of all 'chemical space' is practically impossible. Given this, what are the best strategies for identifying small molecules that modulate biological targets? And how might such strategies differ, depending on whether the primary goal is to understand biological systems or to develop potential drugs?
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
New screening tools for lead compound identificationNature Chemical Biology News and Views (01 Aug 2005)
A new school for screeningNature Biotechnology News and Views (01 Feb 2005)
See all 4 matches for News And Views