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Nature 432, 451-453 (25 November 2004) | doi:10.1038/432451a; Published online 24 November 2004

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Regenerative medicine: Prometheus unbound

Michael D. Schneider1

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The discovery of a protein that stimulates cell migration and survival in damaged mouse hearts suggests a potential new approach to the treatment of heart attacks.

The death of heart muscle cells, unmatched by the generation of replacement cells, is ultimately a basis for death from heart disease. This concept of heart failure as a muscle-cell-deficiency disorder has prompted vigorous investigation of ways to replace or protect the endangered cell, including gene and cell therapies.

  1. Michael D. Schneider is at the Center for Cardiovascular Development, Departments of Medicine, Molecular and Cellular Biology, and Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA.
    Email: michaels@bcm.tmc.edu

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