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News and Views
Nature 432, 281-282 (18 November 2004) | doi:10.1038/432281a; Published online 17 November 2004
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Director, Division of Materials Research
- National Science Foundation
- Arlington, VA
Multimedia Programmer
- Indegene Lifesystems Pvt. Ltd
- Bengaluru 560 071 India
Neurobiology: At the root of brain cancer
Michael F. Clarke1
Abstract
A small subpopulation of cells, 'brain-cancer stem cells', has been identified in humans. They have the exclusive ability to drive tumour formation, and could prove an effective target for therapies.
Brain cancers are among the most devastating tumours in humans and are often rapidly fatal despite aggressive treatments. These tumours typically contain varied populations of cells that differ in the specific proteins — or markers — displayed on the cell surface.
- Michael F. Clarke is in the Departments of Internal Medicine, and Cell and Developmental Biology, University of Michigan Medical School, CSCG Room 4410, 1500 E. Medical School Drive, Ann Arbor, Michigan 48109-0936, USA.
e-mail: Email: mclarke@umich.edu
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