Editorials

Not just academic p1

The Russian Academy of Sciences is failing to provide either the quality of research or the scientific advice that reformers had been hoping for.

doi:10.1038/431001a

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Distributing the costs of climate change p1

Policy-makers must face up to the fact that global warming is creating winners and losers.

doi:10.1038/431001b

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News

Ethics review slams government panels over conflicts of interest p3

Critics decry job-title loophole in committee rules

Emma Marris

doi:10.1038/431003a

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Disaster movie highlights transatlantic divide p4

Cinematic climate future leaves Germans nonplussed and Americans worried

Quirin Schiermeier

doi:10.1038/431004a

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Organizers claim success for Stockholm science jamboree p5

Meeting meshed well with Swedish city

Alison Abbott

doi:10.1038/431005a

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Wildlife campaigners fight planned site for Scripps Florida p5

Governor Jeb Bush wooing massive institute

Rex Dalton

doi:10.1038/431005b

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Thailand faces dilemma over bird flu vaccine p6

Farmers turn to black market to dodge cull

David Cyranoski

doi:10.1038/431006a

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Lab chiefs fear European rules will cost postdoc jobs p6

Scientists' unions want long-term contracts

David Osumi-Sutherland

doi:10.1038/431006b

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Microchip industry proposes broad survey of worker health p7

Critics call for fully independent review

Geoff Brumfiel

doi:10.1038/431007a

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Five-year grant gets bird database off to a flying start p7

Each animal to be automatically mapped

Erika Check

doi:10.1038/431007b

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News in brief p8

doi:10.1038/431008a

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News Features

Climate change: Crunch time for Kyoto p12

Only Russia can rescue the global agreement on climate change. So why aren't Russian climate scientists speaking up? Quirin Schiermeier and Bryon MacWilliams report from Moscow.

doi:10.1038/431012a

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Physics and music: Brothers in art p14

Piers Coleman is a theoretical physicist, his brother Jaz a musician with an unusual pedigree. Together, they want to break down boundaries between science and the arts. Sarah Tomlin attends their latest concert.

doi:10.1038/431014a

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Correspondence

Biosecurity must be internationally supervised p17

US restrictions on cooperation are hampering legitimate microbiological research.

Jan van Aken, Stefan Johannsen and Regine Kollek

doi:10.1038/431017a

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Linnean Society backs Godfray on use of web p17

David Smith

doi:10.1038/431017b

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Need for economists to set global priorities p17

Bjørn Lomborg

doi:10.1038/431017c

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Commentary

Politics, morals and embryos p19

Can bioethics in the United States rise above politics?

doi:10.1038/431019a

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Books and Arts

When giants walked the Earth p21

A pedigree of Dawin's well bred English bulldogs.

Steve Jones reviews A Reason for Everything: Natural Selection and the British Imagination by Marek Kohn

doi:10.1038/431021a

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Well bred rodents p22

Michael Festing reviews Making Mice: Standardizing Animals for American Biomedical Research, 1900–1955 by Karen Rader

doi:10.1038/431022a

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Into the woods p23

Colin Tudge reviews Encyclopedia of Forest Sciences

doi:10.1038/431023a

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New in paperback p23

doi:10.1038/431023b

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Essay

Midsummer madness p25

How an unexpected allegory led to the birth of a new subject.

Gautam R. Desiraju

doi:10.1038/431025a

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News and Views

Astrobiology: Message in a bottle p27

Extraterrestrial civilizations may find it more efficient to communicate by sending material objects across interstellar distances rather than beams of electromagnetic radiation.

Woodruff T. Sullivan, III

doi:10.1038/431027a

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Evolutionary biology:  Time, space and genomes p28

In most animals, the Hox genes — which control development — are clustered together. But why? New evidence supports the idea that the requirement for a temporal order of expression keeps the cluster intact.

Nipam H. Patel

doi:10.1038/431028a

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Statistical physics:  Hear the noise p29

At the nanoscale, thermal fluctuations and noise dominate. But instead of being a hindrance, the details of the noise itself can reveal the physical properties of the system.

Simon Kos and Peter Littlewood

doi:10.1038/431029a

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Cell biology:  Regulated self-cannibalism p31

Cells consume parts of themselves to survive starvation and during development. But how do they control this process of self-eating so that it begins at the right time and does not end up killing the cell?

Daniel J. Klionsky

doi:10.1038/431031a

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Theoretical biology:  Mushrooms in cyberspace p32

Nicholas P. Money

doi:10.1038/431032a

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Planet formation:  The core problem p32

Controversy over shock-wave experiments on the compression of hydrogen has broad implications — for understanding the cores of Jupiter and Saturn, and even the formation of extrasolar planets.

William B. Hubbard

doi:10.1038/431032b

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Cancer:  Cell survival guide p35

A jaded observer might consider the cancer research field near maturity and surprising new results improbable. But work on the protein netrin-1 shows that unforeseen insights into cancer can still occur.

Eric R. Fearon and Kathleen R. Cho

doi:10.1038/431035a

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Astronomy:  The quiet one p35

Alison Wright

doi:10.1038/431035b

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100 and 50 years ago p36

doi:10.1038/431036a

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Research highlights p37

doi:10.1038/431037a

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Brief Communications

Animal behaviour:  Use of dung as a tool by burrowing owls p39

This bird distributes animal dung in and around its burrow to provide a bait for its prey.

Douglas J. Levey, R. Scot Duncan and Carrie F. Levins

doi:10.1038/431039a

First paragraph | Full Text | PDF (370K)

Botany:  A new self-pollination mechanism p39

Yingqiang Wang, Dianxiang Zhang, Susanne S. Renner and Zhongyi Chen

doi:10.1038/431039b

First paragraph | Full Text | PDF (370K)

Brief Communications Arising

Superconductors:  Time-reversal symmetry breaking?

Sergey V. Borisenko, Alexander A. Kordyuk, Andreas Koitzsch, Martin Knupfer, Jörg Fink, Helmuth Berger and Chengtian T. Lin

doi:10.1038/nature02931

First paragraph | Full Text | PDF (357K)

Superconductors:  Time-reversal symmetry breaking? (reply)

Juan C. Campuzano, Adam Kaminski, Stephan Rosenkranz and Helen M. Fretwell

doi:10.1038/nature02932

First paragraph | Full Text | PDF (85K)

Article

Active foundering of a continental arc root beneath the southern Sierra Nevada in California p41

George Zandt, Hersh Gilbert, Thomas J. Owens, Mihai Ducea, Jason Saleeby and Craig H. Jones

doi:10.1038/nature02847

Abstract | Full Text | PDF (789K) | Supplementary information

Letters to Nature

Inscribed matter as an energy-efficient means of communication with an extraterrestrial civilization p47

Christopher Rose and Gregory Wright

doi:10.1038/nature02884

First paragraph | Full Text | PDF (245K) | Supplementary information

See also: News and Views by Sullivan

Spectroscopy of spontaneous spin noise as a probe of spin dynamics and magnetic resonance p49

S. A. Crooker, D. G. Rickel, A. V. Balatsky and D. L. Smith

doi:10.1038/nature02804

First paragraph | Full Text | PDF (478K) | Supplementary information

See also: News and Views by Kos & Littlewood

Negative intrinsic resistivity of an individual domain wall in epitaxial (Ga,Mn)As microdevices p52

H. X. Tang, S. Masmanidis, R. K. Kawakami, D. D. Awschalom and M. L. Roukes

doi:10.1038/nature02809

First paragraph | Full Text | PDF (507K)

Decline of surface temperature and salinity in the western tropical Pacific Ocean in the Holocene epoch p56

Lowell Stott, Kevin Cannariato, Robert Thunell, Gerald H. Haug, Athanasios Koutavas and Steve Lund

doi:10.1038/nature02903

First paragraph | Full Text | PDF (282K) | Supplementary information

Osmium isotopic constraints on the nature of the DUPAL anomaly from Indian mid-ocean-ridge basalts p59

S. Escrig, F. Capmas, B. Dupré and C. J. Allègre

doi:10.1038/nature02904

First paragraph | Full Text | PDF (264K) | Supplementary information

The evolution of müllerian mimicry in multispecies communities p63

Christopher D. Beatty, Kirsten Beirinckx and Thomas N. Sherratt

doi:10.1038/nature02818

First paragraph | Full Text | PDF (240K) | Supplementary information

Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica p67

Hee-Chan Seo, Rolf Brudvik Edvardsen, Anne Dorthea Maeland, Marianne Bjordal, Marit Flo Jensen, Anette Hansen, Mette Flaat, Jean Weissenbach, Hans Lehrach, Patrick Wincker, Richard Reinhardt and Daniel Chourrout

doi:10.1038/nature02709

First paragraph | Full Text | PDF (362K) | Supplementary information

See also: News and Views by Patel

Biological abnormality of impaired reading is constrained by culture p71

Wai Ting Siok, Charles A. Perfetti, Zhen Jin and Li Hai Tan

doi:10.1038/nature02865

First paragraph | Full Text | PDF (486K)

Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein p76

Andreu Casali and Gary Struhl

doi:10.1038/nature02835

First paragraph | Full Text | PDF (315K)

Netrin-1 controls colorectal tumorigenesis by regulating apoptosis p80

Laetitia Mazelin, Agnès Bernet, Christelle Bonod-Bidaud, Laurent Pays, Ségolène Arnaud, Christian Gespach, Dale E Bredesen, Jean-Yves Scoazec and Patrick Mehlen

doi:10.1038/nature02788

First paragraph | Full Text | PDF (438K) | Supplementary information

See also: News and Views by Fearon & Cho

A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response p84

Michael B. Reed, Pilar Domenech, Claudia Manca, Hua Su, Amy K. Barczak, Barry N. Kreiswirth, Gilla Kaplan and Clifton E. Barry, III

doi:10.1038/nature02837

First paragraph | Full Text | PDF (264K)

Involvement of targeted proteolysis in plant genetic transformation by Agrobacterium p87

Tzvi Tzfira, Manjusha Vaidya and Vitaly Citovsky

doi:10.1038/nature02857

First paragraph | Full Text | PDF (343K)

Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos p92

Carrie R. Cowan and Anthony A. Hyman

doi:10.1038/nature02825

First paragraph | Full Text | PDF (454K) | Supplementary information

Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L p96

Déborah Bourc'his and Timothy H. Bestor

doi:10.1038/nature02886

First paragraph | Full Text | PDF (270K)

Transcriptional regulatory code of a eukaryotic genome p99

Christopher T. Harbison, D. Benjamin Gordon, Tong Ihn Lee, Nicola J. Rinaldi, Kenzie D. Macisaac, Timothy W. Danford, Nancy M. Hannett, Jean-Bosco Tagne, David B. Reynolds, Jane Yoo, Ezra G. Jennings, Julia Zeitlinger, Dmitry K. Pokholok, Manolis Kellis, P. Alex Rolfe, Ken T. Takusagawa, Eric S. Lander, David K. Gifford, Ernest Fraenkel and Richard A. Young

doi:10.1038/nature02800

First paragraph | Full Text | PDF (393K) | Supplementary information

Structure of the acrosomal bundle p104

Michael F. Schmid, Michael B. Sherman, Paul Matsudaira and Wah Chiu

doi:10.1038/nature02881

First paragraph | Full Text | PDF (289K) | Supplementary information

Addendum: Pathways towards and away from Alzheimer's disease p107

Mark P. Mattson

doi:10.1038/nature02940

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corrigendum: Sirtuin activators mimic caloric restriction and delay ageing in metazoans p107

Jason G. Wood, Blanka Rogina, Siva Lavu, Konrad Howitz, Stephen L. Helfand, Marc Tatar and David Sinclair

doi:10.1038/nature02941

Full Text | PDF (81K)

Naturejobs

The skills hunt p109

Paul Smaglik

doi:10.1038/nj7004-109a

Full Text | PDF (123K)