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News and Views
Nature 430, 976-977 (26 August 2004) | doi:10.1038/430976a; Published online 25 August 2004
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Chemical biology: Green fluorescent RNA
Michael Famulok1
Abstract
The future for intracellular imaging looks bright with the development of fluorescent probes made entirely of RNA. The cunning design exploits structural attributes of RNA to detect a variety of small molecules.
Green fluorescent protein (GFP) has proven tremendously useful as a method of creating intense visible fluorescence by entirely molecular biological steps1. Generally, the gene encoding GFP is fused with a gene of interest so that the resultant protein is tagged with the fluorescent module.
- Michael Famulok is at the Kekulé Institut für Organische Chemie und Biochemie, University of Bonn, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany.
e-mail: Email: m.famulok@uni-bonn.de
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