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Nature 429, 817-818 (24 June 2004) | doi:10.1038/429817a
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Cell biology: A channel for protein waste
Randy Schekman1
Abstract
Cells destroy misshapen proteins; viruses use the same methods to destroy healthy cellular proteins that are involved in antiviral defences. A long-sought intermediary in the process has now been uncovered.
Cells go to great lengths to ensure that protein molecules fold properly and function in the correct cellular compartment. Mistakes are dealt with harshly: the offending proteins are destroyed.
- Randy Schekman is in the Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA.
e-mail: Email: schekman@berkeley.edu
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