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Nature 429, 351-352 (27 May 2004) | doi:10.1038/429351a

Automata make antisense

Anne Condon1

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Information-carrying DNA strands can be used to perform simple computations, but have so far been little more than toys. Can molecular computers be more broadly useful — in medicine, for instance?

People have long been fascinated with automata, fashioning them from any available materials to create mechanical creatures or musical devices, or to carry out simple computations. The materials used have even included biological molecules: in 2001, for instance, Yaakov Benenson and colleagues1 built a tiny automaton from DNA strands and enzymes.

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