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Nature 428, 271-272 (18 March 2004) | doi:10.1038/428271a
Cancer: Dangerous liaisons
Allan Balmain1 & Rosemary J. Akhurst1
Abstract
The cells of multicellular organisms are highly communicative and so can strongly influence one another's behaviour. One line of communication is particularly important in keeping cell growth in check.
A single cell destined to become a tissue or an organism can't go it alone in its rise to such dizzy heights. Communication, in the form of direct contacts between cells, interactions between cells and their surroundings, or the transmission of biochemical signals, is essential.
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