Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 427, 598 (12 February 2004) | doi:10.1038/427598a
Open Innovation Challenges
-
Efficient Chromosome Doubling: Plant Cell Division
The Seeker is looking for an efficient chromosome doubling method in plants and in particular, metho...
-
Fast Growth of Transformed Soybean Shoots
A method for accelerating growth of soybean shoots is desired.
- More Challenges
- Powered by:
nature jobs
Research Fellows in Pluripotent Stem Cell Technology
- The University of Nottingham
- Nottingham, UK
Faculty Position in Biochemistry
- University of Tuebingen
- Tuebingen 72076 Germany
Molecular biology: Ensuring error-free DNA repair
Tomas Lindahl1
Abstract
Damaged DNA must be removed with the utmost precision, as mistakes are costly. The structure of a repair enzyme bound to its substrate provides a welcome clue to how this is achieved.
Certain forms of oxygen, known as reactive oxygen species, can be deleterious for living organisms. Although most cells can tolerate and even exploit them, these oxygen forms may contribute to cancer, tissue degeneration and ageing.
- Tomas Lindahl is at the Cancer Research UK London Research Institute, Clare Hall Laboratories, South Mimms, Hertfordshire EN6 3LD, UK.
Email: Tomas.Lindahl@cancer.org.uk
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
A novel form of the DNA double helix imposed on the TATA-box by the TATA-binding proteinNature Structural Biology Article (01 Jan 1996)
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylaseNature Letters to Editor (12 Feb 2004)
