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Nature 427, 499-500 (5 February 2004) | doi:10.1038/427499a

Ion channels: Shake, rattle or roll?

Robert O. Blaustein1 & Christopher Miller2

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Nerve transmission depends on voltage-gated ion-channel proteins, which in turn depend on the behaviour of a membrane domain called the voltage sensor. Therein lies the latest episode in a continuing story.

The propagation of electrical signals in the nervous system endows animals with moment-to-moment overall coherence. Without it, worms could not wriggle, flies could not find fruit, and we could not read News and Views.

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