Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 427, 493-494 (5 February 2004) | doi:10.1038/427493a
Medicine: K is for koagulation
J. Evan Sadler1
Abstract
Comparative genetic linkage studies in rats, mice and humans have finally identified a key component of vitamin K metabolism that is targeted by the commonest anticoagulant drugs in use today.
Vitamins have enormous medical and economic importance. For example, the discovery of vitamin K, essential for blood clotting, led to the prevention of countless deaths from bleeding and blood clots, and facilitated the control of devastating agricultural pests.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2Nature Letters to Editor (05 Feb 2004)
Identification of the gene for vitamin K epoxide reductaseNature Letters to Editor (05 Feb 2004)
Common VKORC1 and GGCX polymorphisms associated with warfarin doseThe Pharmacogenomics Journal Original Article
Pseudoxanthoma Elasticum-Like Phenotype with Cutis Laxa and Multiple Coagulation Factor Deficiency Represents a Separate Genetic EntityJournal of Investigative Dermatology Original Article
See all 12 matches for Research