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Nature 427, 493-494 (5 February 2004) | doi:10.1038/427493a
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Assistant / Associate
- University of Missouri
- Columbia MO 65211 United States
Director, UQ Centre for Clinical Research
- University of Queensland, Brisbane, Australia
- Brisbane, Queensland, Australia
Medicine: K is for koagulation
J. Evan Sadler1
Abstract
Comparative genetic linkage studies in rats, mice and humans have finally identified a key component of vitamin K metabolism that is targeted by the commonest anticoagulant drugs in use today.
Vitamins have enormous medical and economic importance. For example, the discovery of vitamin K, essential for blood clotting, led to the prevention of countless deaths from bleeding and blood clots, and facilitated the control of devastating agricultural pests.
- Howard Hughes Medical Institute, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Email: esadler@im.wustl.edu
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