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Nature 424, 896-897 (21 August 2003) | doi:10.1038/424896a

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Cell biology: Metabolism meets death

Julian Downward1

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A protein that controls cell death has been found in a complex with a protein involved in glucose metabolism. Is this a point of contact between these two crucial cellular processes?

All organisms, and all cells, need food to survive: it supplies energy for everything from movement to cell proliferation. But beyond this simple relationship, there is evidence that there is a more direct connection between the molecular pathways that convert food into energy within a cell and the pathways that control whether the cell lives or dies.

  1. Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.
    Email: downward@cancer.org.uk