Table of contents
Volume 423 Number 6943 pp903-1022
Editorials
A flight of fancy p903
Agricultural biotechnology isn't the first promising new technology to become ensnared in trade politics. The same fate buried supersonic commercial air travel — but that time, the boot was on the other foot.
doi:10.1038/423903a
Building bridges p903
Science and technology agreements between the European Union and Arab countries are a small, but welcome step.
doi:10.1038/423903b
News
WHO issues rallying cry to keep fight against SARS on track p905
David Cyranoski
doi:10.1038/423905a
Biologists disappointed as NIH budget falls flat p905
Erika Check
doi:10.1038/423905b
Visa rules leave US colleges facing semester of discontent p906
Geoff Brumfiel
doi:10.1038/423906a
European deal aims to attract Arab scientists p906
Nicola Nosengo
doi:10.1038/423906b
Photos stop as Landsat 7 defies engineers p907
Tony Reichhardt
doi:10.1038/423907a
Dolly firm in trouble after transgenic milk fails to flow p907
Jenny Hogan
doi:10.1038/423907b
Share slump brings biotech firms to government's door p908
Erika Check
doi:10.1038/423908a
Journals wrestle with definition of 'competing' interest p908
Jonathan Knight
doi:10.1038/423908b
India plans to bring neutrino science home p909
K. S. Jayaraman
doi:10.1038/423909a
Discovery changes view of bacteria p909
Jonathan Knight
doi:10.1038/423909b
news feature
AIDS Vaccines: Back to 'plan A' p912
The received wisdom in AIDS vaccine research is that stimulating cellular immunity is more important than producing antibodies. But some experts are now reviving the antibody strategy, says Erika Check.
Erika Check
doi:10.1038/423912a
Atomic physics: Rocky Mountain high p915
Beneath the peaks of Colorado nestles an unusual institute that leads the world in atomic physics. Peter Aldhous visits JILA, where a culture of sharing has underpinned Nobel success.
Peter Aldhous
doi:10.1038/423915a
Correspondence
Dalí and the double helix p917
Science fascinated the great surrealist, who combined it with angels and allegories.
Elena Guardiola and Josep-E. Baños
doi:10.1038/423917a
Crystal: ever-evolving and expanding in scope p917
Russell Seitz
doi:10.1038/423917b
Crystal: clear difference from glass p917
Bruno Contreras Moreira
doi:10.1038/423917c
Crystal: clear difference from glass p918
doi:10.1038/423918a
Online comment could promote unfair criticism p918
Andrew Lumsden, Martin Raff and Joshua R. Sanes
doi:10.1038/423918b
MRC planning outweighs excellence in science p918
Dontcho Staynov
doi:10.1038/423918c
Fiendishly clever? p918
Rupert C. Marshall
doi:10.1038/423918d
Books and Arts
Vision quest p919
A radical theory seeks to overturn current views of how we see the world.
Michael Morgan reviews Why We See What We Do: An Empirical Theory of Vision by Dale Purves and R. Beau Lotto
doi:10.1038/423919a
Discovering geological time p920
David R. Oldroyd reviews The Man Who Found Time: James Hutton and the Discovery of the Earth's Antiquity by Jack Repcheck
doi:10.1038/423920a
Eyes on the prize p921
István Hargittai reviews How to Win the Nobel Prize: An Unexpected Life in Science by J. Michael Bishop
doi:10.1038/423921a
Illustration: A fine body of work p921
Mary Purton
doi:10.1038/423921b
News and Views
Materials science: Synthetic sea shell p925
The mechanical properties of natural substances such as bone and shell are envied by those involved in the fabrication of materials. A 'bricks-and-mortar' structure, assembled layer by layer, is the key to making sea shells.
Michael Rubner
doi:10.1038/423925a
Telomeres: Taking the measure p926
Telomeres — the tips of chromosomes — need to be preserved, and this involves replenishing telomeric DNA when it has been eroded. But telomeres must not become too long, and one aspect of length control is now revealed.
Vicki Lundblad
doi:10.1038/423926a
Atmospheric physics: Electric jets p927
Powerful electric currents have been detected in discharges between thunderclouds and the upper atmosphere. Carried by gigantic jets, they are a new factor in the model of the Earth's electrical and chemical environment.
Victor P. Pasko
doi:10.1038/423927a
100 and 50 years ago p928
doi:10.1038/423928a
Evolution: The battle between the sexes p929
Male–female conflict over mating rate can drive rapid evolution and lead to female refusal to mate with males from other populations, so implicating sexual conflict in the generation of biodiversity.
Tom Tregenza
doi:10.1038/423929a
Catalysis: A greener solution p930
In a 'biphasic' system, a catalyst dissolved in a liquid phase can be recycled if the reaction products are captured in an adjacent phase. A catalyst-storing liquid that is plentiful and environmentally friendly has been found.
Walter Leitner
doi:10.1038/423930a
Neurobiology: Synapses unplugged p931
At the junctions between two neurons, the machinery that releases neurotransmitter from one cell must lie near calcium channels and align with detectors in the receiving cell. We now have a better idea how this occurs.
J. Troy Littleton and Morgan Sheng
doi:10.1038/423931a
Earth science: Spread thin in the Arctic p932
The northernmost segment of the global mid-ocean-ridge system, the Gakkel ridge, is a bit of an oddity. Provocative data are emerging from an international geophysical and geochemical study of the region.
Emily M. Klein
doi:10.1038/423932a
Obituary: Jeff Schell (1935–2003) p934
Marc Van Montagu
doi:10.1038/423934a
news and views in brief p935
doi:10.1038/423935a
Brief Communications
Neuroperception: Facial expressions linked to monkey calls p937
Pulling a face to emphasize a spoken point is not seen as just a human prerogative.
Asif A. Ghazanfar and Nikos K. Logothetis
doi:10.1038/423937a
First paragraph | Full Text | PDF (342K)
Biomechanics: Bacterial flagellar switching under load p938
Karen A. Fahrner, William S. Ryu and Howard C. Berg
doi:10.1038/423938a
First paragraph | Full Text | PDF (99K)
erratum: Rapid change in mouse mitochondrial DNA p938
doi:10.1038/423938b
Articles
-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis p939
Markus Missler, Weiqi Zhang, Astrid Rohlmann, Gunnar Kattenstroth, Robert E. Hammer, Kurt Gottmann and Thomas C. Südhof
doi:10.1038/nature01755
Abstract | Full Text | PDF (1,054K) | Supplementary information
See also: News and Views by Littleton & Sheng
Structure and gating mechanism of the acetylcholine receptor pore p949
Atsuo Miyazawa, Yoshinori Fujiyoshi and Nigel Unwin
doi:10.1038/nature01748
Abstract | Full Text | PDF (654K) | Supplementary information
Magmatic and amagmatic seafloor generation at the ultraslow-spreading Gakkel ridge, Arctic Ocean p956
P. J. Michael, C. H. Langmuir, H. J. B. Dick, J. E. Snow, S. L. Goldstein, D. W. Graham, K. Lehnert, G. Kurras, W. Jokat, R. Mühe and H. N. Edmonds
doi:10.1038/nature01704
Abstract | Full Text | PDF (2,324K)
See also: News and Views by Klein
Letters to Nature
Geophysical evidence for reduced melt production on the Arctic ultraslow Gakkel mid-ocean ridge p962
W. Jokat, O. Ritzmann, M. C. Schmidt-Aursch, S. Drachev, S. Gauger and J. Snow
doi:10.1038/nature01706
First paragraph | Full Text | PDF (1,276K) | Supplementary information
See also: News and Views by Klein
Magnetization distribution in the mixed-phase state of hole-doped manganites p965
Y. Murakami, J. H. Yoo, D. Shindo, T. Atou and M. Kikuchi
doi:10.1038/nature01715
First paragraph | Full Text | PDF (349K)
Three-dimensional binary superlattices of magnetic nanocrystals and semiconductor quantum dots p968
F. X. Redl, K.-S. Cho, C. B. Murray and S. O'Brien
doi:10.1038/nature01702
First paragraph | Full Text | PDF (414K) | Supplementary information
Modulated structure of solid iodine during its molecular dissociation under high pressure p971
Takemura Kenichi, Sato Kyoko, Fujihisa Hiroshi and Onoda Mitsuko
doi:10.1038/nature01724
First paragraph | Full Text | PDF (394K)
Gigantic jets between a thundercloud and the ionosphere p974
H. T. Su, R. R. Hsu, A. B. Chen, Y. C. Wang, W. S. Hsiao, W. C. Lai, L. C. Lee, M. Sato and H. Fukunishi
doi:10.1038/nature01759
First paragraph | Full Text | PDF (254K)
See also: News and Views by Pasko
Uranium series dates from Qesem Cave, Israel, and the end of the Lower Palaeolithic p977
R. Barkai, A. Gopher, S. E. Lauritzen and A. Frumkin
doi:10.1038/nature01718
First paragraph | Full Text | PDF (248K)
The evolution of reproductive isolation through sexual conflict p979
Oliver Y. Martin and David J. Hosken
doi:10.1038/nature01752
First paragraph | Full Text | PDF (162K)
See also: News and Views by Tregenza
Opposing basal ganglia processes shape midbrain visuomotor activity bilaterally p982
Huai Jiang, Barry E. Stein and John G. McHaffie
doi:10.1038/nature01698
First paragraph | Full Text | PDF (380K)
Mapping multiple features in the population response of visual cortex p986
Amit Basole, Leonard E. White and David Fitzpatrick
doi:10.1038/nature01721
First paragraph | Full Text | PDF (540K) | Supplementary information
Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning p990
Makoto Nishiyama, Akemi Hoshino, Lily Tsai, John R. Henley, Yoshio Goshima, Marc Tessier-Lavigne, Mu-ming Poo and Kyonsoo Hong
doi:10.1038/nature01751
First paragraph | Full Text | PDF (475K) | Supplementary information
LAF1 ubiquitination by COP1 controls photomorphogenesis and is stimulated by SPA1 p995
Hak Soo Seo, Jun-Yi Yang, Masaki Ishikawa, Cordelia Bolle, Maria L. Ballesteros and Nam-Hai Chua
doi:10.1038/nature01696
First paragraph | Full Text | PDF (538K)
Enhanced gravi- and phototropism in plant mdr mutants mislocalizing the auxin efflux protein PIN1 p999
Bosl Noh, Anindita Bandyopadhyay, Wendy Ann Peer, Edgar P. Spalding and Angus S. Murphy
doi:10.1038/nature01716
First paragraph | Full Text | PDF (406K) | Supplementary information
Chromosome cohesion is regulated by a clock gene paralogue TIM-1 p1002
Raymond C. Chan, Annette Chan, Mili Jeon, Tammy F. Wu, Danielle Pasqualone, Ann E. Rougvie and Barbara J. Meyer
doi:10.1038/nature01697
First paragraph | Full Text | PDF (707K) | Supplementary information
Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast p1009
May C. Morris, Peter Kaiser, Stanislav Rudyak, Chris Baskerville, Mark H. Watson and Steven I. Reed
doi:10.1038/nature01720
First paragraph | Full Text | PDF (474K) | Supplementary information
POT1 as a terminal transducer of TRF1 telomere length control p1013
Diego Loayza and Titia de Lange
doi:10.1038/nature01688
First paragraph | Full Text | PDF (1,356K) | Supplementary information
See also: News and Views by Lundblad
corrigendum: Non-classical receptive field mediates switch in a sensory neuron's frequency tuning p1018
Maurice J. Chacron, Brent Doiron, Leonard Maler, André Longtin and Joseph Bastian
doi:10.1038/nature01684
addendum: Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1 p1018
Emmanuel Treiner, Livine Duban, Seiamak Bahram, Mirjana Radosavljevic, Valerie Wanner, Florence Tilloy, Pierre Affaticati, Susan Gilfillan and Olivier Lantz
doi:10.1038/nature01700
New on the Market
New for biotechnology p1019
Your Mac for sequence analysis — and MACS for your cell separations.
doi:10.1038/4231019a
Naturejobs
ProspectsMoving targets p1021
Paul Smaglik
doi:10.1038/nj6943-1021a
movers
Movers p1022
doi:10.1038/nj6943-1022a
