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Nature 423, 233-234 (15 May 2003) | doi:10.1038/423233a

Open Innovation Challenges

Genomics: Yeast rises again

Steven L. Salzberg

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What's in a genome? The short answer is that you can't really say in detail for any one species until you have the genome sequences of a variety of other species — some closely related, others less so — to compare it with.

While the human and mouse genomes have lately dominated public discussions of genome science, yeast researchers have quietly continued to forge ahead with analysing Saccharomyces cerevisiae and related yeast species. Yeast has long been a favourite of biologists, who use it as a model for investigating the biology of higher organisms.