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Nature 422, 27-28 (6 March 2003) | doi:10.1038/422027a

Immunology: Fast and feel good?

Vijay K. Kuchroo & Lindsay B. Nicholson

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Claims that fasting eases symptoms of autoimmune disease have been met with scepticism. But the idea receives some support from the finding that leptin, a hormone that controls body weight, also regulates autoimmunity.

Malnourished people present a tempting target for pathogens. Measles, for example, is renowned for being a more serious disease in populations that are starving or close to starving.