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Nature 421, 219-220 (16 January 2003) | doi:10.1038/421219a
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Director, Division of Materials Research
- National Science Foundation
- Arlington, VA
Postdoctoral Fellows
- The Mathematical Biosciences Institute
- Ohio, USA
Sugars tied to the spot
Sabine L. Flitsch & Rein V Ulijn
Abstract
The interactions of sugars and proteins underlie many biological processes, and cataloguing them is a daunting task. A technique for attaching sugars to microarrays offers a promising, high-throughput solution.
Of the three main classes of biopolymers — proteins, nucleic acids and sugars — the sugars, or saccharides, are the most complex and hence the most difficult to study. Each monosaccharide building-block has multiple attachment sites, which means that sugars can be built in a variety of linear or branched fashions.
- Sabine L. Flitsch and Rein V. Ulijn are in the School of Chemistry, University of Edinburgh, Joseph Black Building, West Mains Road, Edinburgh EH9 3JJ, UK.
Correspondence to: e-mail: Email: sabine.flitsch@ed.ac.uk; Email: rein.ulijn@ed.ac.uk
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