Alliance for Cellular Signaling Supplement
Nature 420, 708-710 (12 December 2002) | doi:10.1038/nature01305
Unravelling the signal-transduction network in B lymphocytes
Gilberto R. Sambrano1, Grischa Chandy2, Sangdun Choi3, Dianne Decamp4, Robert Hsueh4, Keng-Mean Lin4, Dennis Mock5, Nancy O'Rourke2, Tamara Roach6, Hongjun Shu4, Bob Sinkovits5, Mary Verghese2 & Henry Bourne1
Abstract
The Alliance for Cellular Signaling has chosen the mouse B lymphocyte as a model system to understand basic principles that govern cellular signalling. Progress to that end has focused initially on establishing a reproducible experimental cell system and characterizing essential signalling responses. Although unravelling this complex network will take years, findings revealed in the interim will prove immensely useful to the scientific community at large.
- Department of Cellular and Molecular Pharmacology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA
- Department of Molecular Pharmacology, Stanford University School of Medicine, 975 California Avenue, Palo Alto, California 94305, USA
- Biology Division, 147-75, California Institute of Technology, Pasadena, California 91125, USA
- Department of Pharmacology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
- San Diego Supercomputer Center, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA
- Department of Rheumatology, San Francisco Veterans Administration Medical Center, 4150 Clement Street, San Francisco, California 94121, USA
Correspondence to: Gilberto R. Sambrano1
Correspondence and requests for materials should be addressed to G.R.S.
(e-mail: Email: sambrano@cmp.ucsf.edu)
