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Nature 419, 347-349 (26 September 2002) | doi:10.1038/419347a

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Membrane transport: The making of a vesicle

Anne A. Schmidt

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The transport of molecules from one cellular compartment to another often requires membrane-bounded carriers. New work gives insight into how the shaping of membrane into such vesicles is linked to the selection of cargo.

If you could look inside your cells you would see several different compartments, delimited by membranes composed of lipids and proteins. You would notice that the compartments are highly dynamic and undergo a series of changes in morphology, allowing small, sack-like structures to bud off from time to time.