Access

News and Views

Nature 419, 120-121 (12 September 2002) | doi:10.1038/419120a

Open Innovation Challenges

  • Optimizing Sub-cellular Localization Tags

    • Deadline: Nov 29 2009
    • Reward: $20,000 USD

    The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....

  • Single-cell Analysis Platform

    • Deadline: Dec 02 2009
    • Reward: $5,000 USD

    This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...

naturejobs

More science jobs
Post a job for free

DNA repair: Right on target with ubiquitin

Cecile M. Pickart

Top

Cellular DNA-repair mechanisms prevent mutations from accumulating, thereby averting defects in cell function. A molecule best known for its role in protein degradation is now shown to have a specific task in DNA repair.

The activity of many of the proteins in our cells depends on the chemical 'labels' that are attached to them. A commonly used label is the ubiquitin molecule, which regulates numerous cellular processes1.