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Nature 418, 731-732 (15 August 2002) | doi:10.1038/418731a
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Professor / Associate Professor (Pharmaceutics / Pharmaceutical Analysis&quality Control)
- Alliance Institute of Advanced Pharmacy and Health Sciences
- Hyderabad 500038 India
Assistant or Associate Professor, Section of Anatomic Pathology
- The Medical College of Georgia
- Augusta, Georgia, USA
Malaria: Mass tool for diagnosis
Matthias Mann
Abstract
Efficient and sensitive methods to determine whether, and to what extent, a person is infected with malaria should help to improve treatment. A high-tech approach, using mass spectrometry, may be the answer.
Years ago my PhD adviser, John Fenn of Yale University, told me that he wanted to develop a mass spectrometer — the well-known tool for identifying and quantifying compounds and for determining their structure — that could be used in the doctor's office. People would deposit their sample in one end of the machine, and out from the other end would come a list of diagnoses based on unambiguous 'digital' mass-spectrometry data.
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