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Nature 418, 287-288 (18 July 2002) | doi:10.1038/418287a
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Four Postdoctoral Fellow Positions – Synchrotron Medical Imaging
- CIHR Team in Synchrotron Medical Imaging
- Saskatchewan, Canada
One Postdoctoral Position at Centre for Research in Agricultural Genomics
- The Centre for Research Agricultural Genomics Consorcio CSIC-IRTA-UAB
- Barcelona Spain
Longevity: Don't hold your breath
Siu Sylvia Lee & Gary Ruvkun
Abstract
In some organisms a reduced-calorie diet increases lifespan. Conventional thinking about the mechanism involved now comes under question from the results of experiments with yeast.
More than sixty years ago a report appeared demonstrating that rats fed a diet containing 30–50% fewer calories live for four years instead of the normal three1. 'Calorie restriction' (CR) has since been shown to extend the lifespan of species ranging from unicellular yeast, to worms and flies, and certain mammals2.
- Siu Sylvia Lee and Gary Ruvkun are in the Department of Genetics, Harvard Medical School, and the Department of Molecular Biology, Massaschusetts General Hospital, Boston, Massachusetts 02114, USA.
Correspondence to: e-mail: Email: ruvkun@molbio.mgh.harvard.edu
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