Access
To read this story in full you will need to login or make a payment (see right).
insight
Nature 415, 198-205 (10 January 2002) | doi:10.1038/415198a
Open Innovation Challenges
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
- More Challenges
- Powered by:
nature jobs
Flash Animator
- Indegene Lifesystems Pvt. Ltd
- Bengaluru 560 071 India
Manager Medical Writitng
- Indegene Lifesystems Pvt. Ltd
- Bengaluru 560 071 India
review article Cardiac excitation–contraction coupling
Donald M. Bers
Abstract
Of the ions involved in the intricate workings of the heart, calcium is considered perhaps the most important. It is crucial to the very process that enables the chambers of the heart to contract and relax, a process called excitation–contraction coupling. It is important to understand in quantitative detail exactly how calcium is moved around the various organelles of the myocyte in order to bring about excitation–contraction coupling if we are to understand the basic physiology of heart function. Furthermore, spatial microdomains within the cell are important in localizing the molecular players that orchestrate cardiac function.
To read this story in full you will need to login or make a payment (see right).
