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Fifty years of inactivation

Nature volume 411, pages 643–644 (2001)Cite this article

Potassium channels can be closed by a process known as inactivation — this is, for instance, how nerve cells regulate firing frequency. Events involved in inactivation are now revealed in unprecedented detail.

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Figure 1: A voltage-dependent potassium channel and the ball-and-chain model of channel inactivation.

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  1. Department of Molecular and Cellular Physiology, the Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, 94305, California, USA

    Richard W. Aldrich

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  1. Richard W. Aldrich
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Correspondence to Richard W. Aldrich.

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Aldrich, R. Fifty years of inactivation. Nature 411, 643–644 (2001). https://doi.org/10.1038/35079705

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