Table of contents
Volume 408 Number 6811 pp389-498
In this issue (23 November 2000)
Opinion
Responses to Alferov p389
The Nobel laureate's prizewinning work was accomplished in the Soviet era, but his example and initiative can help Russia rebuild its science and technology. Philanthropists should take note.
doi:10.1038/35044220
News
Anthropologists in turmoil over allegations of misconduct p391
Rex Dalton
doi:10.1038/35044222
Partners edge closer to vital step on fusion p392
Quirin Schiermeier
doi:10.1038/35044226
French target research money at allaying BSE fears p392
Declan Butler
doi:10.1038/35044229
Europe boosts genome resource centres . . . p393
Alison Abbott
doi:10.1038/35044232
. . . as German genomics gets cash windfall p393
Alison Abbott
doi:10.1038/35044235
Placebos could improve link between medical outlooks p394
Paul Smaglik
doi:10.1038/35044238
Researchers fail to find signs of life in 'living' particles p394
Alison Abbott
doi:10.1038/35044241
Biotech report dubbed 'worthless' p394
Haim Watzman
doi:10.1038/35044243
Governments urged to rethink dam projects p395
Mark Schrope
doi:10.1038/35044245
Aventis gets short shrift over release of modified corn p395
Jessa Netting
doi:10.1038/35044248
News Feature
Russia's prize fighter p398
When Zhores Alferov won a share of this year's Nobel Prize for Physics, he restored pride to Russian science. But can he exploit his celebrity status to move research up the political agenda? Quirin Schiermeier investigates.
Quirin Schiermeier
doi:10.1038/35044254
Fruitfly centre spreads its wings p400
The world's main supplier of exotic Drosophila species has had a poor record for customer service. But, as Rex Dalton found, it is having a facelift that should boost studies of evolutionary genetics.
Rex Dalton
doi:10.1038/35044258
Correspondence
Revolution in references: give readers a chance by putting page numbers p402
Steve Wise
doi:10.1038/35044262
Book Reviews
Speaking in too many tongues p403
Linguists are divided in their ideas about the origin of language.
Massimo Piattelli-Palmarini reviews Human Language and Our Reptilian Brain: The Subcortical Bases of Speech, Syntax, and Thought by Philip Lieberman
doi:10.1038/35044137
Celebrating blurry boundaries p404
Steven Vogel reviews The Extended Organism: The Physiology of Animal-Built Structures by J. Scott Turner
doi:10.1038/35044140
Observations of a travelling naturalist p405
Janet Browne reviews Charles Darwin's Zoology Notes & Specimen Lists from H.M.S. Beagle
doi:10.1038/35044143
Science in culture p406
Martin Kemp reviews
doi:10.1038/35044147
News and Views
Gaining light from silicon p411
Silicon lasers would help computers operate faster by replacing electrical connections with optical ones. The trouble is, normal silicon doesn't glow. Densely packed silicon nanocrystals could be the answer.
Leigh Canham
doi:10.1038/35044156
Gene regulation: Local or global? p412
Modifications to histone proteins were thought to act only locally to control the expression of single genes. But the finding of such changes across the whole genome brings that view into question.
Shelley L. Berger
doi:10.1038/35044160
Chemistry: Clipping the carbon–carbon bond p415
The bonds between two carbon atoms tend to be hard to break. But careful manipulation of the starting material can make the process remarkably easy.
Robert H. Crabtree
doi:10.1038/35044164
100 and 50 years ago p416
doi:10.1038/35044167
Evolutionary biology: Déjà vu p416
A long-term study of fruitflies adds to the evidence that evolution can run backwards. To what extent the genetic underpinnings revert to the original is unclear.
J. J. Bull
doi:10.1038/35044169
Materials science: Pore characterization p417
Vincent Dusastre
doi:10.1038/35044171
Developmental biology: Control by combinatorial codes p419
Studies in fruitflies support the idea that regulatory regions of genes control development by acting as molecular 'computers', calculating cell fate according to the combined effects of several signalling pathways.
Arjumand Ghazi and K. VijayRaghavan
doi:10.1038/35044174
Diabetes: Gene therapy for rats and mice p420
Delivery of an insulin-encoding gene into diabetic rats and mice has helped them to regulate their blood glucose levels. But there are still obstacles to overcome before this approach can be used in humans.
Jerrold M. Olefsky
doi:10.1038/35044177
Molecular electronics: A dual-action material p421
In the drive for smaller electronic components, chemists are thinking on a molecular scale. By combining two simple molecules, a hybrid has been produced that is both magnetic and an electrical conductor.
Fernando Palacio and Joel S. Miller
doi:10.1038/35044179
Anthropology: Lovely grub p422
John Whitfield
doi:10.1038/35044183
Olympus/Nature competition: A 1, 2, 3 in light microscopy p423
The standard of entries in the Olympus and Nature Light Microscopy Competition was extremely high. But there could be only one winner: a stunning image of a dividing newt lung cell.
Graham A. Dunn
doi:10.1038/35044186
Brief Communications
Older bull elephants control young males p425
Orphaned male adolescents go on killing sprees if mature males aren't around.
Rob Slotow, Gus van Dyk, Joyce Poole, Bruce Page and Andre Klocke
doi:10.1038/35044191
First paragraph | Full Text | PDF (231K)
Materials science: C66 fullerene encaging a scandium dimer p426
Chun-Ru Wang, Tsutomu Kai, Tetsuo Tomiyama, Takuya Yoshida, Yuji Kobayashi, Eiji Nishibori, Masaki Takata, Makoto Sakata and Hisanori Shinohara
doi:10.1038/35044195
First paragraph | Full Text | PDF (459K) | Supplementary information
Materials science: A stable non-classical metallofullerene family p427
S. Stevenson, P. W. Fowler, T. Heine, J. C. Duchamp, G. Rice, T. Glass, K. Harich, E. Hajdu, R. Bible and H. C. Dorn
doi:10.1038/35044199
First paragraph | Full Text | PDF (510K) | Supplementary information
Palaeontology: The 'feathers' of Longisquama p428
Robert R. Reisz and Hans-Dieter Sues
doi:10.1038/35044204
First paragraph | Full Text | PDF (249K)
Correction: Detection of preinvasive cancer cells p428
doi:10.1038/35044207
Progress
In search of the tumour-suppressor functions of BRCA1 and BRCA2 p429
Ralph Scully and David M. Livingston
doi:10.1038/35044000
Abstract | Full Text | PDF (188K)
Review
The DNA damage response: putting checkpoints in perspective p433
Bin-Bing S. Zhou and Stephen J. Elledge
doi:10.1038/35044005
Abstract | Full Text | PDF (179K)
Article
Optical gain in silicon nanocrystals p440
L. Pavesi, L. Dal Negro, C. Mazzoleni, G. Franzò and F. Priolo
doi:10.1038/35044012
Abstract | Full Text | PDF (297K) | Supplementary information
Letters to Nature
Evolution of the Sun's large-scale magnetic field since the Maunder minimum p445
S. K. Solanki, M. Schüssler and M. Fligge
doi:10.1038/35044027
First paragraph | Full Text | PDF (185K)
Coexistence of ferromagnetism and metallic conductivity in a molecule-based layered compound p447
Eugenio Coronado, José R. Galán-Mascarós, Carlos J. Gómez-García and Vladimir Laukhin
doi:10.1038/35044035
First paragraph | Full Text | PDF (265K)
See also: News and Views by Palacio & Miller
Direct imaging of the pores and cages of three-dimensional mesoporous materials p449
Yasuhiro Sakamoto, Mizue Kaneda, Osamu Terasaki, Dong Yuan Zhao, Ji Man Kim, Galen Stucky, Hyun June Shin and Ryong Ryoo
doi:10.1038/35044040
First paragraph | Full Text | PDF (397K) | Supplementary information
Improved estimates of global ocean circulation, heat transport and mixing from hydrographic data p453
Alexandre Ganachaud and Carl Wunsch
doi:10.1038/35044048
First paragraph | Full Text | PDF (330K)
The use of earthquake rate changes as a stress meter at Kilauea volcano p457
James Dieterich, Valérie Cayol and Paul Okubo
doi:10.1038/35044054
First paragraph | Full Text | PDF (321K)
Concurrent density dependence and independence in populations of arctic ground squirrels p460
Tim J. Karels and Rudy Boonstra
doi:10.1038/35044064
First paragraph | Full Text | PDF (152K)
Variation in the reversibility of evolution p463
Henrique Teotónio and Michael R. Rose
doi:10.1038/35044070
First paragraph | Full Text | PDF (199K)
See also: News and Views by Bull
Integration of target and body-part information in the premotor cortex when planning action p466
Eiji Hoshi and Jun Tanji
doi:10.1038/35044075
First paragraph | Full Text | PDF (353K) | Supplementary information
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans p470
Rajesh Ranganathan, Stephen C. Cannon and H. Robert Horvitz
doi:10.1038/35044083
First paragraph | Full Text | PDF (366K) | Supplementary information
Notch signalling and the synchronization of the somite segmentation clock p475
Yun-Jin Jiang, Birgit L. Aerne, Lucy Smithers, Catherine Haddon, David Ish-Horowicz and Julian Lewis
doi:10.1038/35044091
First paragraph | Full Text | PDF (302K) | Supplementary information
Binding of disease-associated prion protein to plasminogen p479
Michael B. Fischer, Christiane Roeckl, Petra Parizek, Hans Peter Schwarz and Adriano Aguzzi
doi:10.1038/35044100
First paragraph | Full Text | PDF (207K)
Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue p483
Hyun Chul Lee, Su-Jin Kim, Kyung-Sup Kim, Hang-Cheol Shin and Ji-Won Yoon
doi:10.1038/35044106
First paragraph | Full Text | PDF (373K)
See also: News and Views by Olefsky
A ubiquitin-like system mediates protein lipidation p488
Yoshinobu Ichimura, Takayoshi Kirisako, Toshifumi Takao, Yoshinori Satomi, Yasutsugu Shimonishi, Naotada Ishihara, Noboru Mizushima, Isei Tanida, Eiki Kominami, Mariko Ohsumi, Takeshi Noda and Yoshinori Ohsumi
doi:10.1038/35044114
First paragraph | Full Text | PDF (288K)
G
i and Go are target proteins of
reactive oxygen species p492
Motohiro Nishida, Yoshiko Maruyama, Rie Tanaka, Kenji Kontani, Taku Nagao and Hitoshi Kurose
doi:10.1038/35044120
First paragraph | Full Text | PDF (189K) | Supplementary information
Global histone acetylation and deacetylation in yeast p495
Maria Vogelauer, Jiansheng Wu, Noriyuki Suka and Michael Grunstein
doi:10.1038/35044127
First paragraph | Full Text | PDF (188K)
See also: News and Views by Berger
erratum: An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells p498
David Whyatt, Fokke Lindeboom, Alar Karis, Rita Ferreira, Eric Milot, Rudi Hendriks, Marella de Bruijin, An Langeveld , Joost Gribnau, Frank Grosveld and Sjaak Philipsen
doi:10.1038/35044133
Correction: Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins p498
Anna Lasorella, Michela Noseda, Mercedes Beyna, Yoshifumi Yokota and Antonio Iavarone
doi:10.1038/35044135
