Opinion

Joys of darkness p1

Planetaria are getting ever better at capturing the glories and the challenges of the night sky. They are underused not only in that astronomical context, but for other sciences too.

doi:10.1038/35024219

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News

Britain may boost protection of researchers from intimidation... p3

Natasha Loder

doi:10.1038/35024221

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...as German activists wage propaganda war p3

Quirin Schiermeier

doi:10.1038/35024224

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Construction starts on largest telescope in the south p4

Michael Cherry

doi:10.1038/35024226

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Japan's desire to lead in IT fuels latest budget requests p4

David Cyranoski

doi:10.1038/35024229

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US forest fires send ecology experiments up in smoke p5

Paul Smaglik

doi:10.1038/35024232

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Electricity debt could mean lights out for Russian virus institute p5

Carl Levitin and Alison Abbott

doi:10.1038/35024235

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Californian centre will test medical uses of cannabis p6

Rex Dalton

doi:10.1038/35024238

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Researchers practise martian living in the Canadian Arctic p6

Steve Nadis

doi:10.1038/35024241

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Climate change expert stirs new controversy p7

Paul Smaglik

doi:10.1038/35024244

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US grant glues 'virtual cell' together p7

Paul Smaglik

doi:10.1038/35024247

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CERN considers chasing up hints of Higgs boson p8

Alison Abbott

doi:10.1038/35024249

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News in brief p8

doi:10.1038/35024251

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News Feature

Trouble in the greenhouse p10

Tiny airborne particles affect the Earth's climate, in part by influencing the formation of clouds. But modelling the effects of these aerosols is proving to be one of the thorniest problems in climatology, says Mark Schrope.

Mark Schrope

doi:10.1038/35024254

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Correspondence

Debt and poverty turn a disease into an epidemic p13

Sanjay Basu, Kedar Mate and Paul E. Farmer

doi:10.1038/35024206

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Citation figures suggest that the UK brain drain is a genuine problem p13

Alice Sharp Pierson and Peter Cotgreave

doi:10.1038/35024218

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Commentary

Expert witnesses take the stand p15

Historians of science can play an important role in US public health litigation.

doi:10.1038/35024208

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Book Reviews

Varieties of silly experience p17

Or how to keep your head when all around are losing theirs.

N. David Mermin reviews Voodoo Science: The Road from Foolishness to Fraud by Robert L. Park

doi:10.1038/35024137

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Blowing away the smokescreen p18

Raphael Mechoulam reviews The Science of Marijuana by Leslie L. Iversen

doi:10.1038/35024140

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Lights in the night sky p19

Jay M. Pasachoff reviews Great Comets by Robert Burnham

doi:10.1038/35024144

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Science in culture p20

Philip Ball reviews

doi:10.1038/35024146

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Millennium Essay

Old wine in new bottles p21

An agenda for biology that's in its second century — and still going strong.

Jane Maienschein

doi:10.1038/35024170

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Futures

When I was your age p23

The more things change...

John E. Stith

doi:10.1038/35024172

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News and Views

Archaeology: Talk of cannibalism p25

Incontrovertible evidence of cannibalism has been found at a 900-year-old site in the southwestern United States. Why do horrified critics deny that many societies have found cannibalism acceptable?

Jared M. Diamond

doi:10.1038/35024175

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Chemistry: The smallest fullerene p26

Martin F. Jarrold

doi:10.1038/35024178

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Xenotransplantation: New risks, new gains p27

Jeffrey L. Platt

doi:10.1038/35024181

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100 and 50 years ago p29

doi:10.1038/35024184

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Oceanography: Drifters reveal deep circulation p30

Monika Rhein

doi:10.1038/35024186

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Immunology: RNA editing meets DNA shuffling p31

Ming Tian and Frederick W. Alt

doi:10.1038/35024189

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Chemical physics: Spinning molecules to bits p33

Manish Gupta and Richard N. Zare

doi:10.1038/35024192

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Alzheimer's disease: A partner for presenilin p34

Dale Schenk

doi:10.1038/35024194

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Nanotechnology: Bouncing a C₆₀ ball p35

Leo Kouwenhoven

doi:10.1038/35024197

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Daedalus: Cleaning the cleaner p36

David Jones

doi:10.1038/35024200

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Brief Communications

Tyrosine phosphorylation in plant bending p37

Puckering in a ticklish plant is controlled by dephosphorylation of its actin.

Kazuhisa Kameyama, Yoshiro Kishi, Masanori Yoshimura, Nobuyuki Kanzawa, Masazumi Sameshima and Takahide Tsuchiya

doi:10.1038/35024149

First paragraph | Full Text | PDF (197K)

Structure resolution: Imaging light atoms by X-ray holography p38

Miklós Tegze, Gyula Faigel, Stefano Marchesini, Michel Belakhovsky and Olivier Ulrich

doi:10.1038/35024153

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Neurophysiology: Good memories of bad events in infancy p38

Regina M. Sullivan, Margo Landers, Brian Yeaman and Donald A. Wilson

doi:10.1038/35024156

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Immunology: Investigating T-cell memory p40

Alberto Mantovani

doi:10.1038/35024159

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reply: Investigating T-cell memory p40

Charles H. Maris, Joshy Jacob and David Baltimore

doi:10.1038/35024161

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Review

Microtubule motors in mitosis p41

David J. Sharp, Gregory C. Rogers and Jonathan M. Scholey

doi:10.1038/35024000

Abstract | Full Text | PDF (4,149K) | Supplementary information

Article

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and APP processing p48

Gang Yu, Masaki Nishimura, Shigeki Arawaka, Diane Levitan, Lili Zhang, Anurag Tandon, You-Qiang Song, Ekaterina Rogaeva, Fusheng Chen, Toshitaka Kawarai, Agnes Supala, Lyne Levesque, Haung Yu, Dun-Sheng Yang, Erin Holmes, Paul Milman, Yan Liang, Dong Mei Zhang, Dong Hong Xu, Christine Sato, Evgeny Rogaev, Marsha Smith, Christopher Janus, Yanni Zhang, Ruedi Aebersold, Lindsay Farrer, Sandro Sorbi, Amalia Bruni, Paul Fraser and Peter St George-Hyslop

doi:10.1038/35024009

Abstract | Full Text | PDF (323K) | Supplementary information

See also: News and Views by Schenk

Letters to Nature

Non-quantized penetration of magnetic field in the vortex state of superconductors p55

A. K. Geim, S. V. Dubonos, I. V. Grigorieva, K. S. Novoselov, F. M. Peeters and V. A. Schweigert

doi:10.1038/35024025

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Nanomechanical oscillations in a single-C₆₀ transistor p57

Hongkun Park, Jiwoong Park, Andrew K. L. Lim, Erik H. Anderson, A. Paul Alivisatos and Paul L. McEuen

doi:10.1038/35024031

First paragraph | Full Text | PDF (288K)

See also: News and Views by Kouwenhoven

Gas-phase production and photoelectron spectroscopy of the smallest fullerene, C₂₀ p60

Horst Prinzbach, Andreas Weiler, Peter Landenberger, Fabian Wahl, Jürgen Wörth, Lawrence T. Scott, Marc Gelmont, Daniela Olevano and Bernd v. Issendorff

doi:10.1038/35024037

First paragraph | Full Text | PDF (283K)

See also: News and Views by Jarrold

Chemical characterization of bohrium (element 107) p63

R. Eichler, W. Brüchle, R. Dressler, Ch.E. Düllmann, B. Eichler, H. W. Gäggeler, K. E. Gregorich, D. C. Hoffman, S. Hübener, D. T. Jost, U. W. Kirbach, C. A. Laue, V. M. Lavanchy, H. Nitsche, J. B. Patin, D. Piguet, M. Schädel, D. A. Shaughnessy, D. A. Strellis, S. Taut, L. Tobler, Y. S. Tsyganov, A. Türler, A. Vahle, P. A. Wilk and A. B. Yakushev

doi:10.1038/35024044

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Mid-depth recirculation observed in the interior Labrador and Irminger seas by direct velocity measurements p66

Kara L. Lavender, Russ E. Davis and W. Brechner Owens

doi:10.1038/35024048

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See also: News and Views by Rhein

Earthquakes as beacons of stress change p69

Leonardo Seeber and John G. Armbruster

doi:10.1038/35024055

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The earliest known sauropod dinosaur p72

Eric Buffetaut, Varavudh Suteethorn, Gilles Cuny, Haiyan Tong, Jean Le Loeuff, Sasidhorn Khansubha and Sutee Jongautchariyakul

doi:10.1038/35024060

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Biochemical evidence of cannibalism at a prehistoric Puebloan site in southwestern Colorado p74

Richard A. Marlar, Banks L. Leonard, Brian R. Billman, Patricia M. Lambert and Jennifer E. Marlar

doi:10.1038/35024064

First paragraph | Full Text | PDF (381K)

See also: News and Views by Diamond

Uptake of dissolved organic carbon and trace elements by zebra mussels p78

Hudson A. Roditi, Nicholas S. Fisher and Sergio A. Sañudo-Wilhelmy

doi:10.1038/35024069

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Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS p81

Shuji Shigenobu, Hidemi Watanabe, Masahira Hattori, Yoshiyuki Sakaki and Hajime Ishikawa

doi:10.1038/35024074

First paragraph | Full Text | PDF (205K) | Supplementary information

Cloned pigs produced by nuclear transfer from adult somatic cells p86

Irina A. Polejaeva, Shu-Hung Chen, Todd D. Vaught, Raymond L. Page, June Mullins, Suyapa Ball, Yifan Dai, Jeremy Boone, Shawn Walker, David L. Ayares, Alan Colman and Keith H. S. Campbell

doi:10.1038/35024082

First paragraph | Full Text | PDF (344K) | Supplementary information

See also: News and Views by Platt

Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice p90

Luc J.W. van der Laan, Christopher Lockey, Bradley C. Griffeth, Francine S. Frasier, Carolyn A. Wilson, David E. Onions, Bernhard J. Hering, Zhifeng Long, Edward Otto, Bruce E. Torbett and Daniel R. Salomon

doi:10.1038/35024089

First paragraph | Full Text | PDF (184K)

See also: News and Views by Platt

AT₁-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration p94

Said AbdAlla, Heinz Lother and Ursula Quitterer

doi:10.1038/35024095

First paragraph | Full Text | PDF (423K) | Supplementary information

Pilus retraction powers bacterial twitching motility p98

Alexey J. Merz, Magdalene So and Michael P. Sheetz

doi:10.1038/35024105

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TFIIH is negatively regulated by cdk8-containing mediator complexes p102

Sasha Akoulitchev, Sergei Chuikov and Danny Reinberg

doi:10.1038/35024111

First paragraph | Full Text | PDF (277K) | Supplementary information

Domain-specific recruitment of amide amino acids for protein synthesis p106

Debra L. Tumbula, Hubert D. Becker, Wei-zhong Chang and Dieter Söll

doi:10.1038/35024120

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erratum: Atomically defined mechanism for proton transfer to a buried redox centre in a protein p110

Kaisheng Chen, Judy Hirst, Raul Camba, Christopher A. Bonagura, C. David Stout, Barbara K. Burgess and Fraser A. Armstrong

doi:10.1038/35024131

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correction: The duration of antigen receptor signalling determines CD4 ⁺ versus CD8⁺ T-cell lineage fate p110

Koji Yasutomo, Carolyn Doyle, Lucio Miele, Chana Fuchs and Ronald N. Germain

doi:10.1038/35024133

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correction: The DNA sequence of human chromosome 21 p110

and The chromosome 21 mapping and sequencing consortium

doi:10.1038/35024135

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New on the Market

Proteins, peptides, proteomics p111

A 10-fold boost for a proteomics package, and new ways with detection.

doi:10.1038/35024164

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Careers and Recruitment

Research gets a new lease of life as Canada takes the initiative p113

After years of cuts, Canadian science is finally receiving the financial backing it needs to flourish in the 21st century, says Diane Gershon.

doi:10.1038/35024211

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Canada catalyses health research with thirteen virtual institutes p113

Diane Gershon

doi:10.1038/35024216

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