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Nature ${rb.getVolume()}, 351-352 (23 March 2000) | doi:10.1038/35006158;

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Y-chromosome variation and Irish origins

Ireland's position on the western edge of Europe suggests that the genetics of its population should have been relatively undisturbed by the demographic movements that have shaped variation on the mainland. We have typed 221 Y chromosomes from Irish males for seven (slowly evolving) biallelic and six (quickly evolving) simple tandem-repeat markers. When these samples are partitioned by surname, we find significant differences in genetic frequency between those of Irish Gaelic and of foreign origin, and also between those of eastern and western Irish origin. Connaught, the westernmost Irish province, lies at the geographical and genetic extreme of a Europe-wide cline.

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