In a DNA computer, the input and output are both strands of DNA. A computer in which the strands are attached to the surface of a chip can now solve difficult problems quite quickly.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
DNA biomolecular-electronic encoder and decoder devices constructed by multiplex biosensors
NPG Asia Materials Open Access 18 January 2012
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Conan Doyle, A. The Sign of Four in The Complete Sherlock Holmes (Barnes & Noble, Dayton, New Jersey, 1988).
Liu, Q. et al. Nature 403, 175–179 (2000).
Adleman, L. M. Science 266, 1021–1024 ( 1994).
Schöning, U. in Proc. 40th Ann. IEEE Conf. Found. Comp. Sci. (FOCS) 410–414 (IEEE Comp. Sci., Los Alamitos, California, 1999).
Adleman, L. in DIMACS Series in Discrete Mathematics and Theoretical Computer Science Vol. 44 (eds Lipton, R. & Baum, E.) 1– 21 (Am. Math. Soc., Providence, Rhode Island, 1996).
Frutos, A. G. et al. Nucleic Acids Res. 25, 4748– 4757 (1997).
Adleman, L. M. Sci. Am. 279, 54–61 ( 1998).
Winfree, E., Liu, F. R., Wenzler, L. A. & Seeman, N. C. Nature 394, 539–544 ( 1998).
Ogihara, M. & Ray, A. in DIMACS Series in Discrete Mathematics and Theoretical Computer Science Vol. 48. (eds Rubin, H. & Wood, D.) 255–264 (Am. Math. Soc., Providence, Rhode Island, 1999).
Ogihara, M. & Ray, A. Algorithmica 25, 239–250 (1999).
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
About this article
Cite this article
Ogihara, M., Ray, A. DNA computing on a chip. Nature 403, 143–144 (2000). https://doi.org/10.1038/35003071
Issue Date:
DOI: https://doi.org/10.1038/35003071
This article is cited by
-
Encoding information into polymers
Nature Reviews Chemistry (2018)
-
Construction of DNA-based logic gates on nanostructured microelectrodes
Nuclear Science and Techniques (2017)
-
DNA biomolecular-electronic encoder and decoder devices constructed by multiplex biosensors
NPG Asia Materials (2012)