Table of contents
Volume 402 Number 6762 pp563-702
Opinion
Building on failed planetary missions p563
The apparent failure of a Mars probe underscores NASA's difficulties in pursuing planetary exploration. Planetary scientists must be allowed to build a credible programme of missions on the bedrock of continuing public support.
doi:10.1038/45012
Wise progress with embryos p563
New guidelines should reduce the scale of ethical dilemmas in embryo research.
doi:10.1038/45014
News
NASA facing awkward questions as hopes for Mars lander fade p565
Tony Reichhardt and Alison Abbott
doi:10.1038/45016
France to lift embryo research ban? p565
Declan Butler
doi:10.1038/45019
Indian patent law will protect crops 'unless injurious to health' p566
K. S. Jayaraman
doi:10.1038/45021
EU candidate states impress with Framework proposals p566
Natasha Loder
doi:10.1038/45024
US close to funding stem-cell work p566
Paul Smaglik
doi:10.1038/45027
Columbia extends support for 'mainstream' Biosphere 2 p567
Rex Dalton
doi:10.1038/45029
US trade rules seek to balance health and patent protection p567
Meredith Wadman and Michael Cherry
doi:10.1038/45032
AAAS to honour 'persecuted' Ukrainian marine biologist p568
Natasha Loder
doi:10.1038/45034
Berlin places genomics among top funding priorities p568
Quirin Schiermeier
doi:10.1038/45036
French plan to exploit genome sparks row ... p569
Declan ButlerD
doi:10.1038/45039
... while Japanese sequencers feel neglected p569
Asako Saegusa
doi:10.1038/45042
Japan pulls its fusion research together ... p570
Asako Saegusa
doi:10.1038/45044
... as Europeans lobby for reactor construction p570
Alison Abbott
doi:10.1038/45046
News Analysis
US food-safety body hears protests over genetically modified food p571
The US Food and Drug Administration is holding public meetings to listen to critics of genetically modified food. Some fear the move may backfire.
Colin Macilwain
doi:10.1038/45049
Correspondence
Seeking clarity in the debate over the safety of GM foods p575
Mark Tester
doi:10.1038/45054
Seeking clarity in the debate over the safety of GM foods p575
Steve L. Taylor and Susan L. Hefle
doi:10.1038/45056
Seeking clarity in the debate over the safety of GM foods p575
Mae-Wan Ho
doi:10.1038/45058
Why Diamond should go to Daresbury p576
John R. Helliwell
doi:10.1038/45060
Seeking a guide to the quality of web writing p576
Roger Elliott and Mark S. Frankel
doi:10.1038/45062
How ethical principles can aid research p576
Joël Sternheimer
doi:10.1038/45064
Lobbying groups must be trustworthy p576
Ketil Haarstad
doi:10.1038/45066
Commentary
Expressing a consensus on candour p577
If governments are to define deception as research misconduct, science deserves clarity and rigour in the definition.
doi:10.1038/45068
Book Reviews
The Church's route to enlightenment p579
George V. Coyne reviews The Sun in the Church: Cathedrals as Solar Observatories by J. L. Heilbron
doi:10.1038/45070
Opening the lines of communication p580
Petra Werner reviews Science under Socialism: East Germany in Comparative Perspective
doi:10.1038/45074
Hidden wealth of data in the depths p581
Franciscus Colijn and Sebastian Lippemeier review From Monsoons to Microbes: Understanding the Ocean's Role in Human Health
doi:10.1038/45076
A multilingual view of the sea p581
doi:10.1038/45079
Story of an obsession p581
Colin L. Masters reviews Prion Biology and Diseases
doi:10.1038/45081
Science in culture p582
Bonnie Hurren and Robert Meech review The Brain
doi:10.1038/45083
Millennium Essay
The forgotten menace p583
Nuclear weapons stockpiles still represent the biggest threat to civilization.
Paul Doty
doi:10.1038/45086
Futures
Spawn of Satan? p585
Widespread egg donation has led to a generation of superkids.
Nicola Griffith
doi:10.1038/45089
News and Views
Quantum optics: Giving a boost to atoms p587
Matter waves can now be amplified in the same way that a laser amplifies light. Such matter-wave amplifiers will be essential for future developments in atom optics, and may be the basis of better and brighter atom lasers.
Kristian Helmerson
doi:10.1038/45092
Alzheimer's disease: The tangled tale of tau p588
E. Mandelkow
doi:10.1038/45095
Volcanology: Magma fragmentation in eruptions p589
Dork Sahagian
doi:10.1038/45099
100 and 50 years ago p592
doi:10.1038/45102
Ecology: Water fleas on cycles p592
James P. Grover
doi:10.1038/45104
Oceanography: Climate and the Gulf Stream p593
Jean-Claude Duplessy
doi:10.1038/45107
Cell biology: Glutamate primes the pump p595
Patrik Rorsman and Erik Renström
doi:10.1038/45110
Nuclear physics: Taking serious risks seriously p596
Sheldon L. Glashow and Richard Wilson
doi:10.1038/45114
Neurobiology: The topography of memory p597
Howard Eichenbaum
doi:10.1038/45117
Molecular motors: Spotting the goods trains p598
Christopher Surridge
doi:10.1038/45120
Astrophysics: Chaotic planet formation p599
Renu Malhotra
doi:10.1038/45123
Daedalus: Citing to infinity p600
David Jones
doi:10.1038/45125
Brief Communications
Coral growing on North Sea oil rigs p601
These installations are home to thriving colonies of an endangered cold-water coral.
Niall Bell and Jan Smith
doi:10.1038/45127
First paragraph | Full Text | PDF (131K)
Evolution: Conservation of a sex-determining gene p601
Craig A. Smith, Peter J. McClive, Patrick S. Western, Kirsty J. Reed and Andrew H. Sinclair
doi:10.1038/45130
First paragraph | Full Text | PDF (131K)
Bioenergetics: Proton pumping by cytochrome c oxidase p602
Hartmut Michel
doi:10.1038/45133
First paragraph | Full Text | PDF (107K)
reply: Bioenergetics: Proton pumping by cytochrome c oxidase p603
M. I. Verkhovsky, A. Jasaitis, M. L. Verkhovskaya, J. E. Morgan and M. Wikström
doi:10.1038/45135
Microporous materials: Electrochemically grown photonic crystals p603
Paul V. Braun and Pierre Wiltzius
doi:10.1038/45137
addendum: Colour categories in a stone-age tribe p604
doi:10.1038/45140
corrections: Magnet levitation at your fingertips p604
doi:10.1038/45142
corrections: Tropical tree gene flow and seed dispersal p604
doi:10.1038/45142
Articles
The role of stress transfer in earthquake occurrence p605
Ross S. Stein
doi:10.1038/45144
Abstract | Full Text | PDF (885K)
Distribution of spatial and nonspatial information in dorsal hippocampus p610
Robert E. Hampson, John D. Simeral and Sam A. Deadwyler
doi:10.1038/45154
Abstract | Full Text | PDF (276K)
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration p615
Gentry N. Patrick, Lawrence Zukerberg, Margareta Nikolic, Suzanne de la Monte, Pieter Dikkes and Li-Huei Tsai
doi:10.1038/45159
Abstract | Full Text | PDF (392K)
Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand p623
José Tormo, Kannan Natarajan, David H. Margulies and Roy A. Mariuzza
doi:10.1038/45170
Abstract | Full Text | PDF (731K)
Letters to Nature
Early planet formation as a trigger for further planet formation p633
Philip J. Armitage and Brad M. S. Hansen
doi:10.1038/45179
First paragraph | Full Text | PDF (364K)
The formation of Uranus and Neptune in the Jupiter–Saturn region of the Solar System p635
Edward W. Thommes, Martin J. Duncan and Harold F. Levison
doi:10.1038/45185
First paragraph | Full Text | PDF (398K) | Supplementary information
First-order phase transitions in a quantum Hall ferromagnet p638
Vincenzo Piazza,
Vittorio Pellegrini,
Fabio Beltram,
Werner Wegscheider,
Tomá
Jungwirth
and
Allan H. MacDonald
doi:10.1038/45189
First paragraph | Full Text | PDF (202K)
Phase-coherent amplification of atomic matter waves p641
S. Inouye, T. Pfau, S. Gupta, A. P. Chikkatur, A. Görlitz, D. E. Pritchard and W. Ketterle
doi:10.1038/45194
First paragraph | Full Text | PDF (209K)
Weaker Gulf Stream in the Florida Straits during the Last Glacial Maximum p644
Jean Lynch-Stieglitz, William B. Curry and Niall Slowey
doi:10.1038/45204
First paragraph | Full Text | PDF (263K)
A criterion for the fragmentation of bubbly magma based on brittle failure theory p648
Youxue Zhang
doi:10.1038/45210
First paragraph | Full Text | PDF (134K)
Tube pumices as strain markers of the ductile–brittle transition during magma fragmentation p650
J. Martí, C. Soriano and D. B. Dingwell
doi:10.1038/45219
First paragraph | Full Text | PDF (198K)
Large-amplitude cycles of Daphnia and its algal prey in enriched environments p653
Edward McCauley, Roger M. Nisbet, William W. Murdoch, Andre M. de Roos and William S. C. Gurney
doi:10.1038/45223
First paragraph | Full Text | PDF (143K)
Ghrelin is a growth-hormone-releasing acylated peptide from stomach p656
Masayasu Kojima, Hiroshi Hosoda, Yukari Date, Masamitsu Nakazato, Hisayuki Matsuo and Kenji Kangawa
doi:10.1038/45230
First paragraph | Full Text | PDF (239K)
Central inputs mask multiple adult neural networks within a single embryonic network p660
Yves Le Feuvre, Valérie S. Fénelon and Pierre Meyrand
doi:10.1038/45238
First paragraph | Full Text | PDF (754K)
Short-term memory in olfactory network dynamics p664
Mark Stopfer and Gilles Laurent
doi:10.1038/45244
First paragraph | Full Text | PDF (289K) | Supplementary information
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons p669
James A. Bibb, Gretchen L. Snyder, Akinori Nishi, Zhen Yan, Laurent Meijer, Allen A. Fienberg, Li-Huei Tsai, Young T. Kwon, Jean-Antoine Girault, Andrew J. Czernik, Richard L. Huganir, Hugh C. Hemmings, Jr, Angus C. Nairn and Paul Greengard
doi:10.1038/45251
First paragraph | Full Text | PDF (217K)
Induction of autophagy and inhibition of tumorigenesis by beclin 1 p672
Xiao Huan Liang, Saadiya Jackson, Matthew Seaman, Kristy Brown, Bettina Kempkes, Hanina Hibshoosh and Beth Levine
doi:10.1038/45257
First paragraph | Full Text | PDF (351K)
Binding of paxillin to 
4 integrins modifies integrin-dependent biological responses p676
Shouchun Liu, Sheila M. Thomas, Darren G. Woodside, David M. Rose, William B. Kiosses, Martin Pfaff and Mark H. Ginsberg
doi:10.1038/45264
First paragraph | Full Text | PDF (359K) | Supplementary information
A novel nuclear export activity in HIV-1 matrix protein required for viral replication p681
Stefan Dupont, Natalia Sharova, Caryn DéHoratius, Ching-Man A. Virbasius, Xiaochun Zhu, Alice G. Bukrinskaya, Mario Stevenson and Michael R. Green
doi:10.1038/45272
First paragraph | Full Text | PDF (463K)
Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis p685
Pierre Maechler and Claes B. Wollheim
doi:10.1038/45280
First paragraph | Full Text | PDF (376K)
The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors p689
Thomas Beck and Michael N. Hall
doi:10.1038/45287
First paragraph | Full Text | PDF (190K)
Eukaryotic type II chaperonin CCT interacts with actin through specific subunits p693
Oscar Llorca, Elizabeth A. McCormack, Gillian Hynes, Julie Grantham, Jacqueline Cordell, José L. Carrascosa, Keith R. Willison, José J. Fernandez and José M. Valpuesta
doi:10.1038/45294
First paragraph | Full Text | PDF (303K) | Supplementary information
Modified reaction centres oxidize tyrosine in reactions that mirror photosystem II p696
L. Kálmán, R. LoBrutto, J. P. Allen and J. C. Williams
doi:10.1038/45300
First paragraph | Full Text | PDF (141K)
New on the Market
Cell biologicals p701
The last New on the Market before Christmas... but no last-minute gift ideas.
doi:10.1038/45306
