FIGURE 1. Some of the brain structures affected by drugs of abuse.

From the following article:

Drug addiction: bad habits add up

Trevor W. Robbins and Barry J. Everitt

Nature 398, 567-570(15 April 1999)

doi:10.1038/19208

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The mesolimbic dopamine system originates in the ventral tegmental area (VTA) of the midbrain, and projects to the nucleus accumbens (NA). The amygdala (A), hippocampus (HC) and medial prefrontal cortex (PFC) send excitatory projections to the nucleus accumbens. C, caudate nucleus (striatum).

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