Table of contents


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Opinion

Opportunity in Kyoto for a president's legacy p527

The success or failure of global climate negotiations rests on the shoulders of Bill Clinton, who can enhance his stature by holding his nerve in the face of industry's scare-mongering.

doi:10.1038/39118


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News

Nobel panel rewards prion theory after years of heated debate p529

Harriet Coles

doi:10.1038/39120


Japan agrees on target for climate curbs p529

doi:10.1038/39123


Congress warns NASA not to raid science funds p530

Tony Reichhardt

doi:10.1038/39125


Surveyor maps desert valleys of Mars p530

doi:10.1038/39127


UK's greenhouse reduction target 'hard but feasible' p530

Ehsan Masood

doi:10.1038/39130


US target 'likely to equal 1990 emissions' p531

Colin Macilwain

doi:10.1038/39132


Public rejects sceptics' line on global warming p531

Colin Macilwain

doi:10.1038/39135


Cash-strapped ANZAAS is set for closure p532

Peter Pockley

doi:10.1038/39137


Plagiarism claims turn spotlight on US Navy's misconduct policy p532

Rex Dalton

doi:10.1038/39140


French labs funded by 'big science' cuts p533

Declan Butler

doi:10.1038/39142


German research agencies feel the pinch p533

Quirin Schiermeier

doi:10.1038/39145


NCI apologizes for fallout study delay p534

Meredith Wadman

doi:10.1038/39147


Gene-modified crop sabotaged in Ireland p534

Anthony Garvey

doi:10.1038/39149


Shortcircuit leads India to abandon Internet satellite p535

K. S. Jayaraman

doi:10.1038/39152


Head of Third World biotechnology centre in Delhi resigns p535

K. S. Jayaraman

doi:10.1038/39154


Asia-Pacific forum backs life science network p535

David Swinbanks

doi:10.1038/39157


Plant genome initiative wins $40m support from Congress p536

doi:10.1038/39159


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Correspondence

Monkey business in space p537

David O. Wiebers, Andrzej Elzanowski, Paul W. Gikas, Jennifer Leaning and Roger D. White

doi:10.1038/39162


Bet you didn't know that p537

Raymond Fink

doi:10.1038/39164


Definition of a gene p537

Christopher D. Epp

doi:10.1038/39166


Science studies misjudged? p538

Andrew Pickering

doi:10.1038/39168


Narrowness in science p538

G. Wilse Robinson and Vera Bongertz

doi:10.1038/39170


Duplications in nomenclature p539

Michael Hortsch

doi:10.1038/39172


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News and Views

Patterns in the sand p541

Paul Umbanhowar

doi:10.1038/39174


Kainate receptors:  Finding homes at synapses p542

Mark Mayer

doi:10.1038/39177


Climate change:  Volcanic sulphur in the balance p543

Michael R. Carroll

doi:10.1038/39180


Linguistics:  The language steamrollers p544

Jared M. Diamond

doi:10.1038/39184


Developmental biology:  Straight and wiggly affinities p546

Peter A. Lawrence

doi:10.1038/39188


Chemotaxis:  On the crest of a spiral wave p547

Alison Mitchell

doi:10.1038/39191


Avoided object:  The negatives of sound p548

doi:10.1038/39194


Gamma-ray astronomy:  Bursts make new waves p548

Bohdan Paczyski and Chryssa Kouveliotou

doi:10.1038/39200


Signal transduction:  Feedback from inhibitory SMADs p549

Malcolm Whitman

doi:10.1038/39202


100 and 50 years ago p549

doi:10.1038/39205


Telomerase:  Cancer and the knockout mouse p551

David Wynford-Thomas and David Kipling

doi:10.1038/39207


The end-replication problem p551

David Wynford-Thomas and David Kipling

doi:10.1038/39210


Daedalus:  Smooth ascent p552

David Jones

doi:10.1038/39213


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Scientific Correspondence

Systemic signalling in gene silencing p553

Olivier Voinnet and David C. Baulcombe

doi:10.1038/39215


A pandemic warning? p554

J. C. de Jong, E. C. J. Claas, A. D. M. E. Osterhaus, R. G. Webster and W. L. Lim

doi:10.1038/39218


Conical beams from open nanotubes p554

Yahachi Saito, Koji Hamaguchi, Koichi Hata, Kunio Uchida, Yoshiharu Tasaka, Fumikazu Ikazaki, Motoo Yumura, Atsuo Kasuya and Yuichiro Nishina

doi:10.1038/39221


DNA fingerprinting from single cells p555

I. Findlay, A. Taylor, P. Quirke, R. Frazier and A. Urquhart

doi:10.1038/39225


Archaeopteryx -like skull in Enantiornithine bird p556

Larry D. Martin and Zhonghe Zhou

doi:10.1038/39228


Top

Book Reviews

Mental modules on the brain p557

P. N. Johnson-Laird

doi:10.1038/39231


Homage to Patagonia p557

doi:10.1038/39233


Old views of the past p558

Nicholas J. Saunders

doi:10.1038/39236


Wing commanders p559

Ernst Hafen

doi:10.1038/39240


Doing the right thing? p560

John Galloway

doi:10.1038/39243


New in paperback p560

doi:10.1038/39245


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Reviews

Molecular motors: structural adaptations to cellular functions p561

Joe Howard

doi:10.1038/39247


Constraints on flux rates and mantle dynamics beneath island arcs from Tonga–Kermadec lava geochemistry p568

Simon Turner and Chris Hawkesworth

doi:10.1038/39257


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Letters to Nature

Competition between randomizing impacts and inelastic collisions in granular pattern formation p574

Troy Shinbrot

doi:10.1038/39264


Induced long-range order in crosslinked 'one-dimensional' stacks of fluid monolayers p576

Gerald C. L. Wong, Wim H. de Jeu, Henry Shao, Keng S. Liang and Rudolf Zentel

doi:10.1038/39271


Origin of rubber-like behaviour in metal alloys p579

Xiaobing Ren and Kazuhiro Otsuka

doi:10.1038/39277


Bending and buckling of carbon nanotubes under large strain p582

M. R. Falvo, G. J. Clary, R. M. Taylor, II, V. Chi, F. P. Brooks, Jr, S. Washburn and R. Superfine

doi:10.1038/39282


Synthesis of cadmium sulphide superlattices using self-assembled bacterial S-layers p585

Wayne Shenton, Dietmar Pum, Uwe B. Sleytr and Stephen Mann

doi:10.1038/39287


Convergent total synthesis of a tumour-associated mucin motif p587

Dalibor Sames, Xiao-Tao Chen and Samuel J. Danishefsky

doi:10.1038/39292


Magma mixing as a source for Pinatubo sulphur p591

Victor Kress

doi:10.1038/39299


Fitness loss and germline mutations in barn swallows breeding in Chernobyl p593

Hans Ellegren, Gabriella Lindgren, Craig R. Primmer and Anders Pape Møller

doi:10.1038/39303


How the brain learns to see objects and faces in an impoverished context p596

R. J. Dolan, G. R. Fink, E. Rolls, M. Booth, A. Holmes, R. S. J. Frackowiak and K. J. Friston

doi:10.1038/39309


A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission p599

Vernon R. J. Clarke, Barbara A. Ballyk, Ken H. Hoo, Allan Mandelzys, Andrew Pellizzari, Catherine P. Bath, Justyn Thomas, Erica F. Sharpe, Ceri H. Davies, Paul L. Ornstein, Darryle D. Schoepp, Rajender K. Kamboj, Graham L. Collingridge, David Lodge and David Bleakman

doi:10.1038/39315


Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease p603

Tony Wyss-Coray, Eliezer Masliah, Margaret Mallory, Lisa McConlogue, Kelly Johnson-Wood, Carol Lin and Lennart Mucke

doi:10.1038/39321


An epithelial serine protease activates the amiloride-sensitive sodium channel p607

Vronique Vallet, Ahmed Chraibi, Hans-Peter Gaeggeler, Jean-Daniel Horisberger and Bernard C. Rossier

doi:10.1038/39329


Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function p610

K. Teoman Uysal, Sarah M. Wiesbrock, Michael W. Marino and Gkhan S. Hotamisligil

doi:10.1038/39335


Control of compartmental affinity boundaries by Hedgehog p614

Isabel Rodriguez and Konrad Basler

doi:10.1038/39343


Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1 p618

Marcus Kretzschmar, Jacqueline Doody and Joan Massagu

doi:10.1038/39348


Smad6 inhibits signalling by the TGF-beta superfamily p622

Takeshi Imamura, Masao Takase, Ayako Nishihara, Eiichi Oeda, Jun-ichi Hanai, Masahiro Kawabata and Kohei Miyazono

doi:10.1038/39355


Daughters against dpp modulates dpp organizing activity in Drosophila wing development p627

Kazuhide Tsuneizumi, Takuya Nakayama, Yuko Kamoshida, Thomas B. Kornberg, Jan L. Christian and Tetsuya Tabata

doi:10.1038/39362


Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling p631

Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn, Takuya Nakayama, Jan L. Christian, Rainer Heuchel, Susumu Itoh, Masahiro Kawabata, Nils-Erik Heldin, Carl-Henrik Heldin and Peter ten Dijke

doi:10.1038/39369


Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic p636

David M. Baorto, Zhimin Gao, Ravi Malaviya, Michael L. Dustin, Anton van der Merwe, Douglas M. Lublin and Soman N. Abraham

doi:10.1038/39376


Mitotic chromatin regulates phosphorylation of Stathmin/Op18 p640

Søren S. L. Andersen, Anthony J. Ashford, Rgis Tournebize, Olivier Gavet, Andr Sobel, Anthony A. Hyman and Eric Karsenti

doi:10.1038/39382


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New on the Market

Tools for biomedical research labs p644

Offering up a variety of devices and reagents for biomedical sciences, this edition includes a single-cell superfusion system, a bioluminescence assay for monitoring cell-cell interactions, and a cell sizer and counter.
compiled by Brendan Horton from information provided by the manufacturers.c b B H f i p b t

doi:10.1038/39388


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