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Nature 389, 239-242 (18 September 1997) | doi:10.1038/38410

Gene therapy - promises, problems and prospects

Inder M. Verma1 & Nikunj Somia1

In principle, gene therapy is simple: putting corrective genetic material into cells alleviates the symptoms of disease. In practice, considerable obstacles have emerged. But, thanks to better delivery systems, there is hope that the technique will succeed.