Table of contents


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Opinion

Malaria initiative needs drug industry's backing p699

The pharmaceutical industry must get behind recent efforts by science funding agencies to coordinate an international attack on malaria.


Hope for science on the subcontinent p699

Fifty years after independence, India and Pakistan are still struggling to develop strength in science.


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News

Funding assured for international malaria sequencing project p701

Declan Butler


Europe's poorer regions woo researchers p701

Alison Abbott


UK watchdog boosts science credentials p702

David Dickson


Management problems prompt Canadian utility to shut reactors p702

David Spurgeon


$100m payout after drug data withheld p703

Meredith Wadman


'Action needed to counter bioterrorism' p703

Meredith Wadman


Ecologists urged to 'win climate debate' p704

Colin Macilwain


Miami AIDS researcher denies charges over billing irregularities p704

Rex Dalton


US-Cuba row over insects goes to weapons meeting p705

Declan Butler


Royal observatory could return to Greenwich site p705

Ehsan Masood


News in Brief p706


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Correspondence

Public-sector patents on human DNA p709

S. M. Thomas, N. Birtwistle, M. Brady and J. F. Burke


Keeping a balance p709

Hermann Bondi


Wisdom in physiology p709

Alexander Maryanovich


Ain't misbehavin' p710

Jim Stevenson


Faraway Faraday p710

John Meurig Thomas


Skewed citations p710

Martin Rees


Natural name selection p710

James Murray


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Commentary

Australian innovation under threat p711


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News and Views

The right sort of roughness p713

Peter Carpenter


Apoptosis CED-4 is a stranger no more p714

Michael O. Hengartner


Microporous solids Cobalt caged for catalysis p715

Robert L. Bedard


Neurodegeneration A silent channel opens its gates p716

Peter H. Seeburg


100 and 50 years ago p717


Atomic physics Shaping atoms in optical lattices p719

Christopher Monroe


Galactic structure Bar serves cosmic scorpion p719

Karen Southwell


Protein folding Folding with a two-stroke motor p720

George Lorimer


Demography Death and the demon drink in Russia p723

Tim Lincoln


Immunology Inside the gearbox of the dendritic cell p724

Colin Watts


Daedalus Magnetic autoeroticism p725

David Jones


Obituary John Zachary Young (1907-97) p726

John Messenger


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Scientific Correspondence

Hyperactive antifreeze protein from beetles p727

Laurie A. Graham, Yih-Cherng Liou, Virginia K. Walker and Peter L. Davies


Role of CED-4 in the activation of CED-3 p728

Arul M. Chinnaiyan, Divya Chaudhary, Karen O'Rourke, Eugene V. Koonin and Vishva M. Dixit


Vaccination onto bare skin p729

De-chu Tang, Zhongkai Shi and David, T. Curiel


Seeing where your hands are p730

Giuseppe di Pellegrino, Elisabetta Làdavas and Alessandro Farné


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Book Reviews

New narratives of creation p731

Andrew H. Knoll reviews Life: An Unauthorized Biography by Richard Fortey


It's a colourful world p731


Watching the neutrinos p732


Fabric of the Universe p732

F. D. Kahn reviews Shadow of a Star: The Neutrino Story of Supernova 1987A by Alfred K. Mann


Tomato-watching in a dark corner p733

Michael Morgan reviews Readings on Color: Volume 1 – The Philosophy of Color; Volume 2 – The Science of Color edited by Alex Byrne and David R. Hilbert


Mind over chatter p734

David Poeppel reviews The Symbolic Species: The Co-Evolution of Language and the Brain by Terrence Deacon


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Articles

Hydrothermal syntheses and structural characterization of zeolite analogue compounds based on cobalt phosphate p735

Pingyun Feng, Xianhui Bu and Galen D. Stucky


The crystal structure of the asymmetric GroEL–GroES–(ADP)7 chaperonin complex p741

Zhaohui Xu, Arthur L. Horwich and Paul B. Sigler


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Letters to Nature

Faint X-ray sources in the core of the globular cluster M28 p751

R. Danner, S. R. Kulkarni, Y. Saito and N. Kawai


Turbulent drag reduction by passive mechanisms p753

L. Sirovich and S. Karlsson


Large-scale production of single-walled carbon nanotubes by the electric-arc technique p756

C. Journet, W. K. Maser, P. Bernier, A. Loiseau, M. Lamy de la Chapelle, S. Lefrant, P. Deniard, R. Lee and J. E. Fischer


Enantioseparation using apoenzymes immobilized in a porous polymeric membrane p758

Brinda B. Lakshmi and Charles R. Martin


Torsional oscillations and the magnetic field within the Earth's core p760

Stephen Zatman and Jeremy Bloxham


Self-similarity of extinction statistics in the fossil record p764

Ricard V. Solé, Susanna C. Manrubia, Michael Benton and Per Bak


Genetic tagging of humpback whales p767

Per J. Palsbøll, Judith Allen, Martine Bérube´, Phillip J. Clapham, Tonnie P. Feddersen, Philip S. Hammond, Richard R. Hudson, Hanne Jørgensen, Steve Katona, Anja Holm Larsen, Finn Larsen#, Jon Lien, David K. Mattila, Jóhann Sigurjónsson, Richard Sears, Tim Smith, Renate Sponer, Peter Stevick and Nils Øien


Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene p769

Jian Zuo, Philip L. De Jager, Kanji A. Takahashi, Weining Jiang, David J. Linden and Nathaniel Heintz


A second endogenous cannabinoid that modulates long-term potentiation p773

Nephi Stella, Paul Schweitzer and Daniele Piomelli


Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta p778

Jiangming Luo, Robert Sladek, Jo-Ann Bader, Annie Matthyssen, Janet Rossant and Vincent Giguère


Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells p782

Marina Cella, Anneke Engering, Valerie Pinet, Jean Pieters and Antonio Lanzavecchia


Developmental regulation of MHC class II transport in mouse dendritic cells p787

Philippe Pierre, Shannon J. Turley, Evelina Gatti, Michael Hull, Joseph Meltzer, Asra Mirza, Kayo Inaba, Ralph M. Steinman and Ira Mellman


Distinct actions of cis and trans ATP within the double ring of the chaperonin GroEL p792

Hays S. Rye, Steven G. Burston, Wayne A. Fenton, Joseph M. Beechem, Zhaohui Xu, Paul B. Sigler and Arthur L. Horwich


DNA renaturation activity of the SMC complex implicated in chromosome condensation p798

Takashi Sutani and Mitsuhiro Yanagida


Metal ion catalysis during splicing of premessenger RNA p801

Erik J. Sontheimer, Sengen Sun and Joseph A. Piccirilli


A second catalytic metal ion in a group I ribozyme p805

Lara B. Weinstein, B. C. N. M. Jones, Richard Cosstick and Thomas R. Cech


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Correspondence

Correction CO2 fixation and photoevolution of H2 and O2 in a mutant of Chlamydomonas lacking photosystem I p808

E. Greenbaum, J. W. Lee, C. V. Tevault, S. L. Blankinship and L. J. Mets


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New on the Market

Molecular means and methods p809

Items on view at the meeting of the American Society for Biochemistry and Molecular Biology in San Francisco may include a versatile hybridization oven, affinity purification reagents and a dual-laser-induced fluorescence detector.

compiled by Brendan Horton from information provided by the manufacturers.


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