| | Opinion |  |
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| | A research council for Europe? 321
Everybody is anxious to help mould Europe's research policy. The place to start is to say that episodic funding (by means of 'framework' programmes) is a bad idea. What is needed is a truly European research council.
doi:10.1038/378321a0
PDF (222K)
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| | Global warming rows 322
The Intergovernmental Panel on Climate Change must reorganize its work-programme in everybody's interest.
doi:10.1038/378322a0
PDF (248K)
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| | China comes cleaner 322
China's bid to join the World Trade Organization does not mean that it is yet a modern state.
doi:10.1038/378322b0
PDF (248K)
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| | News | |
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| | AIDS vaccine 'needs focused effort' as drug firms back off research 323
Declan Butler
doi:10.1038/378323a0
PDF (587K)
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| | Swiss role in EU research will remain limited 323
Oliver Klaffke
doi:10.1038/378323b0
PDF (305K)
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| | Black scientist faces inquiry at South African university 324
Michael Cherry
doi:10.1038/378324a0
PDF (297K)
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| | US space agency escapes the worst of cuts 325
Tony Reichhardt
doi:10.1038/378325a0
PDF (622K)
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| | NIH discovers who counts as 'essential' 325
Adrianne Appel & Colin Macilwain
doi:10.1038/378325b0
PDF (622K)
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| | Biosafety rules will regulate international GMO transfers 326
Ehsan Masood
doi:10.1038/378326a0
PDF (619K)
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| | Swiss researchers adopt voluntary rules on exports 326
David Dickson
doi:10.1038/378326b0
PDF (619K)
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| | Guidelines may boost gene therapy in Japan 327
Stephen Barker
doi:10.1038/378327a0
PDF (273K)
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| | Livermore loses supercomputers to Berkeley 327
Sally Lehrman
doi:10.1038/378327b0
PDF (273K)
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| | Review for radiation effects research 327
doi:10.1038/378327c0
PDF (273K)
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| | Europe tries again on biotechnology patents 328
Alison Abbott
doi:10.1038/378328a0
PDF (278K)
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| | Agronomist quits in funding protest 328
Alison Abbott
doi:10.1038/378328b0
PDF (278K)
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| | Pakistan's scientists respond warily to World Bank reforms 329
Ehsan Masood
doi:10.1038/378329a0
PDF (283K)
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| | Climate critics claim access blocked to unpublished data 329
Colin Macilwain
doi:10.1038/378329b0
PDF (283K)
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| | Correspondence | |
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| | Atomic energy in Pakistan 330
Zia Mian
doi:10.1038/378330a0
PDF (278K)
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| | Atomic energy in Pakistan 330
Pervez Hoodbhoy
doi:10.1038/378330b0
PDF (278K)
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| | Residents' rights 330
Michael Lardelli
doi:10.1038/378330c0
PDF (278K)
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| | News and Views |  |
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| | Patterns of pattern formation 331
As participants at Nature's conference "Patterns of Life" (Boston, 9−10 November) found, moves to different organisms and even to biochemistry are helping to sustain the drive to understand how different body plans develop.
Nicholas Short
doi:10.1038/378331a0
PDF (279K)
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| | On the wings of Pegasus 332
Gordon Walker
doi:10.1038/378332a0
References | PDF (563K)
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| | Astronomical questions of origin and survival 333
Adam Burrows & Jonathan Lunine
doi:10.1038/378333a0
References | PDF (252K)
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neu tack on neuregulin 334
Mark A. Marchionni
doi:10.1038/378334a0
References | PDF (782K)
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| | Hopes for Hofmeister 335
V. Adrian Parsegian
doi:10.1038/378335a0
References | PDF (548K)
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| | Nitric oxide and bad behaviour 336
Harriet Coles
doi:10.1038/378336a0
PDF (287K)
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| | The thrombin paradox 337
John H. Griffin
doi:10.1038/378337a0
References | PDF (713K)
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| | An open or shut case? 338
Everett L. Shock
doi:10.1038/378338a0
References | PDF (701K)
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| | Thanks for the memory 339
Nasser Peyghambarian
doi:10.1038/378339a0
References | PDF (696K)
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| | De-twinkled stars 340
David Jones
doi:10.1038/378340a0
PDF (326K)
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| | Scientific Correspondence | |
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| | Passing round the standards 341
David L. Hawksworth & Paul M. Kirk
doi:10.1038/378341a0
References | PDF (260K)
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| | Tuning stochastic resonance 341
André J. Noest
doi:10.1038/378341b0
PDF (260K)
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| | Tuning stochastic resonance 341
J. J. Collins, Carson C. Chow & Thomas T. Imhoff
doi:10.1038/378341c0
References | PDF (503K)
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| | Toxic mutants in Charcot's sclerosis 342
Don W. Cleveland, Nigel Laing, Patricia V. Hurse & Robert H. Brown Jr
doi:10.1038/378342a0
References | PDF (510K)
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| | Toxic mutants in Charcot's sclerosis 343
Richard W. Orrell, Jaqueline de Belleroche, Stefan L. Marklund, Frances A. Bowe & Robert A. Hallewell
doi:10.1038/378343a0
PDF (267K)
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| | Origin of yaws in the Pleistocene 343
Bruce M. Rothschild, Israel Hershkovitz & Christine Rothschild
doi:10.1038/378343b0
References | PDF (503K)
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| | Legume nitrogen fixation and drought 344
T. R. Sinclair & R. Serraj
doi:10.1038/378344a0
References | PDF (250K)
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| | Book Reviews |  |
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| | The artful scientist 345
L. Pearce Williams reviews Science and Culture: Popular and Philosophical Essays
By
Hermann von Helmholtz
doi:10.1038/378345a0
PDF (311K)
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| | Algal aesthetics 346
G. E. Fogg reviews Freshwater Algae: Their Microscopic World Explored
By
Hilda Canter-Lund & John W. G. Lund
doi:10.1038/378346a0
PDF (431K)
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| | Conservation biology defined 347
Katherine Rails reviews A Primer of Conservation Biology
By
Richard B. Primack and Principles of Conservation Biology
By
Gary K. Meffe & C. Ronald Carroll and Conservation Biology in Theory and Practice
By
Graeme Caughley & Anne Gunn and Encyclopedia of Environmental Biology
Edited by
William Nierenberg
doi:10.1038/378347a0
PDF (534K)
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| | Seeing the light of day (at last) 348
Peter Knight reviews Optical Coherence and Quantum Optics
By
Leonard Mandel & Emil Wolf
doi:10.1038/378348a0
PDF (270K)
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| | Review Article | |
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| | The first 85 million years of avian evolution 349
Luis M. Chiappe
doi:10.1038/378349a0
Abstract & References | PDF (1,806K)
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| | Article |  |
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| | A Jupiter-mass companion to a solar-type star 355
Michel Mayor & Didier Queloz
doi:10.1038/378355a0
Abstract & References | PDF (1,018K)
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| | Letters | |
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| | Unusually strong intramolecular magnetic coupling in a chromium hydride cluster 359
Robert A. Heintz, Thomas F. Koetzle, Robert L. Ostrander, Arnold L. Rheingold, Klaus H. Theopold & Ping Wu
doi:10.1038/378359a0
First paragraph & References | PDF (835K)
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| | Noise-induced enhancement of signal transduction across voltage-dependent ion channels 362
Sergey M. Bezrukov & Igor Vodyanoy
doi:10.1038/378362a0
First paragraph & References | PDF (607K)
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| | Effect of high salt concentrations on water structure 364
R. Leberman & A. K. Soper
doi:10.1038/378364a0
First paragraph & References | PDF (800K)
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| | Liquid-crystalline phases as templates for the synthesis of mesoporous silica 366
George S. Attard, Joanna C. Glyde & Christine G. Göltner
doi:10.1038/378366a0
First paragraph & References | PDF (976K)
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| | Constraints on the origins of hydrocarbon gas from compositions of gases at their site of origin 368
Leigh C. Price & Martin Schoell
doi:10.1038/378368a0
First paragraph & References | PDF (1,083K)
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| | Radiocarbon evidence for extensive plate-boundary rupture about 300 years ago at the Cascadia subduction zone 371
Alan R. Nelson, Brian F. Atwater, Peter T. Bobrowsky, Lee-Ann Bradley, John J. Clague, Gary A. Carver, Mark E. Darienzo, Wendy C. Grant, Harold W. Krueger, Rodger Sparks, Thomas W. Stafford Jr & Minze Stuiver
doi:10.1038/378371a0
First paragraph & References | PDF (1,420K)
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| | Quartz dissolution by the sponge Chondrosia reniformis (Porifera, Demospongiae) 374
Giorgio Bavestrello, Attilio Arillo, Umberto Benatti, Carlo Cerrano, Riccardo Cattaneo-Vietti, Luciano Cortesognoi, Laura Gaggero, Marco Giovine, Michela Tonetti & Michele Sarà
doi:10.1038/378374a0
First paragraph & References | PDF (713K)
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| | A recent common ancestry for human Y chromosomes 376
Michael F. Hammer
doi:10.1038/378376a0
First paragraph & References | PDF (628K)
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| | Sequence variation of the human Y chromosome 379
L. Simon Whitfield, John E. Sulston & Peter N. Goodfellow
doi:10.1038/378379a0
First paragraph & References | PDF (480K)
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| | Stereoscopic depth perception at high velocities 380
M. J. Morgan & E. Castet
doi:10.1038/378380a0
First paragraph & References | PDF (986K)
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| | Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase 383
Randy J. Nelson, Gregory E. Demas, Paul L. Huang, Mark C. Fishman, Valina L. Dawson, Ted M. Dawson & Solomon H. Snyder
doi:10.1038/378383a0
First paragraph & References | PDF (959K)
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| | Multiple essential functions of neuregulin in development 386
Dirk Meyer & Carmen Birchmeier
doi:10.1038/378386a0
First paragraph & References | PDF (1,548K)
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| | Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor 390
Martin Gassmann, Franca Casagranda, Donata Orioli, Horst Simon, Cary Lai, Rüdiger Klein & Greg Lemke
doi:10.1038/378390a0
First paragraph & References | PDF (1,540K)
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| | Requirement for neuregulin receptor erbB2 in neural and cardiac development 394
Kuo-Fen Lee, Horst Simon, Hua Chen, Brian Bates, Mien-Chie Hung & Christopher Hauser
doi:10.1038/378394a0
First paragraph & References | PDF (1,438K)
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| | A huntingtin-associated protein enriched in brain with implications for pathology 398
Xiao-Jiang Li, Shi-Hua Li, Alan H. Sharp, Frederick C. Nucifora, Gabriele Schilling, Anthony Lanahan, Paul Worley, Solomon H. Snyder & Christopher A. Ross
doi:10.1038/378398a0
First paragraph & References | PDF (1,052K)
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| | Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias 403
Yvon Trottier, Yves Lutz, Giovanni Stevanin, Georges Imbert, Didier Devys, Géraldine Cancel, Frédéric Saudou, Chantal Weber, Gilles David, Laszlo Tora, Yves Agid, Alexis Brice & Jean-Louis Mandel
doi:10.1038/378403a0
First paragraph & References | PDF (1,085K)
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| | Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II 406
Joseph E. Dinchuk, Bruce D. Car, Richard J. Focht, Jennifer J. Johnston, Bruce D. Jaffee, Maryanne B. Covington, Nancy R. Contel, Vicki M. Eng, Robert J. Collins, Philip M. Czerniak, Stewart A. Gorry & James M. Trzaskos
doi:10.1038/378406a0
First paragraph & References | PDF (1,247K)
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| | Involvement of Ral GTPase in v-Src-induced phospholipase D activation 409
Hong Jiang, Jing-Qing Luo, Takeshi Urano, Paul Frankel, Zhimin Lu, David A. Foster & Larry A. Feig
doi:10.1038/378409a0
First paragraph & References | PDF (1,069K)
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| | Conversion of thrombin into an anticoagulant by protein engineering 413
C. S. Gibbs, S. E. Coutré, M. Tsiang, W-X. Li, A. K. Jain, K. E. Dunn, V. S. Law, C. T. Mao, S. Y. Matsumura, S. Y. Mejza, L. R. Paborsky & L. L. K. Leung
doi:10.1038/378413a0
First paragraph & References | PDF (878K)
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| | A protein catalytic framework with an N-terminal nucleophile is capable of self-activation 416
James A. Brannigan, Guy Dodson, Helen J. Duggleby, Peter C. E. Moody, Janet L. Smith, Diana R. Tomchick & Alexey G. Murzin
doi:10.1038/378416a0
First paragraph & References | PDF (967K)
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| | Corrections | |
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| | MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia 419
J. Bernhagen, T. Calandra, R. A. Mitchell, S. B. Martin, K. J. Tracey, W. Voelter, K. R. Manogue, A. Cerami & R. Bucala
doi:10.1038/378419a0
PDF (243K)
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| | Crucial role of the pre-T-cell receptor  gene in development of  but not  § T cells 419
Hans Jörg Fehling, Anna Krotkova, Claude Saint-Ruf & Harald von Boehmer
doi:10.1038/378419b0
PDF (243K)
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| | Immunological function of a defined T-cell population tolerized to low-affinity self antigens 419
Kazuhiro Kawai & Pamela S. Ohashi
doi:10.1038/378419c0
PDF (243K)
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| | Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus
419
Yoshiki Sasai, Bin Lu, Herbert Steinbeisser & Eddy M. De Robertis
doi:10.1038/378419d0
PDF (243K)
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| | Erratum | |
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| | Protein molecules as computational elements in living cells 419
Dennis Bray
doi:10.1038/378419e0
PDF (243K)
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| | Letter | |
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| | A base pair between tRNA and 235 rRNA in the peptidyl transferase centre of the ribosome 419
Raymond R. Samaha, Rachel Green & Harry F. Noller
doi:10.1038/378419f0
PDF (243K)
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| | Product Review | |
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| | Cybernation 420
This edition covers new computer hardware and software, including a portable workstation, data-logging and acquisition hardware, imaging software, and on-line and CD-ROM information.
Brendan Horton
doi:10.1038/378420a0
PDF (1,102K)
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