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Mycoplasma infection of cultured cells

Mycoplasma contamination is tough to detect and even more difficult to eradicate. It is best to start over fresh from clean cell stocks, but several elimination options are available.

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References

  1. McGarrity, G.J. Adv. Cell Culture 2, 99–131 (1982).

    Article  Google Scholar 

  2. DelGuidice, R.A. & Gardella, R.S. Tissue Culture Association Monograph 5, 104–115 (US Tissue Culture Association, Gaithersburg, Maryland, 1984).

    Google Scholar 

  3. Chen, T.R. Expl Cell Res. 104, 255–263 (1977).

    Article  CAS  Google Scholar 

  4. Russell, W.C., Newman, C. & Williamson, D.H. Nature 253, 461–462 (1975).

    Article  ADS  CAS  Google Scholar 

  5. Barile, M.F. & Grabowski, M.W. Meth. Mycoplasmol. 2, 173–181 (1983).

    Article  Google Scholar 

  6. McGarrity, G.J. & Carson, D.A. Expl Cell Res. 139, 199–205 (1982).

    Article  CAS  Google Scholar 

  7. Gabridge, M.E., Lundin, D.J. & Gladd, M.F. In Vitro Cell Dev. Biol. 22, 491–498 (1986).

    Article  CAS  Google Scholar 

  8. Hay, R.J. Analyt. Biochem. 171, 225–237 (1988).

    Article  CAS  Google Scholar 

  9. Jeansson, S. & Brorson, J.K. Expl Cell Res. 161, 181–188 (1985).

    Article  CAS  Google Scholar 

  10. Van Diggelen, O.P., Shin, S. & Phillips, D.M. Cancer Res. 37, 2680–2687 (1977).

    CAS  PubMed  Google Scholar 

  11. Schimmelpfeng, L., Langenberg, U. & Peters, H.J. Nature 285, 661–662 (1980).

    Article  ADS  CAS  Google Scholar 

  12. Marcus, M., Lavi, U., Nattenberg, A., Rottem, S., & Markowitz, O. Nature 285, 659–661 (1980).

    Article  ADS  CAS  Google Scholar 

  13. Hay, R.J. Prog. Cancer Res. Ther. 29, 3–21 (1984).

    Google Scholar 

  14. Borup-Christensen, P., Erb, K. & Jensen, J.C. J. Immunol. Meth. 110, 237–240 (1988).

    Article  CAS  Google Scholar 

Download references

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Hay, R., Macy, M. & Chen, T. Mycoplasma infection of cultured cells. Nature 339, 487–488 (1989). https://doi.org/10.1038/339487a0

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