Nature 294, 447 - 449 (03 December 1981); doi:10.1038/294447a0

The path of axons in Drosophila wings in relation to compartment boundaries

John Palka, Margrit Schubiger & H. Stephen Hart

Department of Zoology, University of Washington, Seattle, Washington 98195, USA

We have tested the hypothesis that the paths taken by sensory axons in the peripheral nervous system of Drosophila are influenced by the boundaries between developmental compartments¹. It has been proposed that differences in cell affinity keep the epidermal cells of adjacent compartments from intermingling². Such differences in cell affinity might well also prevent the axons of sensory neurones, which are derived from the same populations as epidermal cells and which use them as growth substrates, from crossing compartment boundaries. However, as we report here, we have found that sensory axons in the wing of Drosophila do cross the boundary between the anterior and posterior compartments of the wing.

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