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Genomic transcriptional activity and the structure of chromatin

Nature volume 260, pages 495–500 (1976)Cite this article

Abstract

Nucleic acid hybridisation has shown that micrococcal nuclease-derived chromatin submits from the cells of Xenopus laevis contain fragments of ribosomal 28S, 18S and 5S RNAs within the population of 200 base-pair pieces of DNA. Subunits from cultured embryonic cells actively transcribing ribosomal RNA contain only 70–74% of the cistronspresent in undigested wild-type DNA, while subunits from adult erythrocytes not active in RNA transcription contain close to 90% of the ribosomal cistrons in native chromatin.

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Authors and Affiliations

  1. Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada, V6T 1W5

    Raymond Reeves & Alma Jones

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  1. Raymond Reeves
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  2. Alma Jones
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Reeves, R., Jones, A. Genomic transcriptional activity and the structure of chromatin. Nature 260, 495–500 (1976). https://doi.org/10.1038/260495a0

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